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Pathway | ID | Enriched_genes | Background genes | P_Value | Corrected P_Value |
---|---|---|---|---|---|
intracellular | GO:0005622 | 1645 | 7395 | 2.07E-144 | 1.52E-140 |
organelle | GO:0043226 | 1541 | 6685 | 1.27E-143 | 4.65E-140 |
intracellular part | GO:0044424 | 1602 | 7135 | 3.48E-142 | 8.51E-139 |
membrane-bounded organelle | GO:0043227 | 1448 | 6166 | 1.6E-137 | 2.93E-134 |
cell | GO:0005623 | 1776 | 8537 | 7.64E-135 | 1.07E-131 |
cell part | GO:0044464 | 1773 | 8516 | 8.74E-135 | 1.07E-131 |
cytoplasm | GO:0005737 | 1289 | 5440 | 8.95E-120 | 9.36E-117 |
intracellular organelle | GO:0043229 | 1397 | 6164 | 1.61E-119 | 1.47E-116 |
metabolic process | GO:0008152 | 1329 | 5837 | 6.62E-113 | 5.39E-110 |
cellular process | GO:0009987 | 1639 | 8082 | 1.39E-109 | 1.02E-106 |
intracellular membrane-bounded organelle | GO:0043231 | 1279 | 5588 | 1.17E-108 | 7.77E-106 |
organic substance metabolic process | GO:0071704 | 1228 | 5477 | 1.85E-97 | 1.13E-94 |
cellular metabolic process | GO:0044237 | 1176 | 5228 | 7.02E-93 | 3.96E-90 |
primary metabolic process | GO:0044238 | 1172 | 5235 | 2.72E-91 | 1.42E-88 |
cytoplasmic part | GO:0044444 | 916 | 3723 | 4.2E-85 | 2.05E-82 |
binding | GO:0005488 | 1300 | 6265 | 4.46E-84 | 2.04E-81 |
intracellular organelle part | GO:0044446 | 931 | 3923 | 1.37E-79 | 5.92E-77 |
organelle part | GO:0044422 | 941 | 3995 | 3.92E-79 | 1.6E-76 |
macromolecule metabolic process | GO:0043170 | 1016 | 4548 | 1.09E-75 | 4.22E-73 |
cellular macromolecule metabolic process | GO:0044260 | 940 | 4220 | 2.96E-68 | 1.09E-65 |
single-organism process | GO:0044699 | 1308 | 6770 | 1.24E-66 | 4.31E-64 |
nitrogen compound metabolic process | GO:0006807 | 778 | 3346 | 3.55E-61 | 1.18E-58 |
protein metabolic process | GO:0019538 | 674 | 2763 | 1.68E-58 | 5.34E-56 |
cellular nitrogen compound metabolic process | GO:0034641 | 734 | 3151 | 1.7E-57 | 5.2E-55 |
catalytic activity | GO:0003824 | 749 | 3313 | 2.13E-54 | 6.23E-52 |
macromolecular complex | GO:0032991 | 641 | 2674 | 4.78E-53 | 1.35E-50 |
cellular protein metabolic process | GO:0044267 | 612 | 2503 | 7.38E-53 | 2E-50 |
biosynthetic process | GO:0009058 | 680 | 2975 | 3.3E-50 | 8.64E-48 |
single-organism cellular process | GO:0044763 | 1113 | 5898 | 4.13E-49 | 1.04E-46 |
organic substance biosynthetic process | GO:1901576 | 666 | 2913 | 4.36E-49 | 1.07E-46 |
cellular biosynthetic process | GO:0044249 | 656 | 2857 | 8.19E-49 | 1.94E-46 |
nucleus | GO:0005634 | 737 | 3386 | 4.76E-48 | 1.09E-45 |
extracellular region part | GO:0044421 | 480 | 1827 | 8.83E-48 | 1.96E-45 |
vesicle | GO:0031982 | 453 | 1701 | 3.01E-46 | 6.48E-44 |
cellular component organization or biogenesis | GO:0071840 | 655 | 2921 | 9.68E-46 | 2.03E-43 |
membrane-bounded vesicle | GO:0031988 | 439 | 1634 | 1.43E-45 | 2.92E-43 |
organonitrogen compound metabolic process | GO:1901564 | 340 | 1118 | 3.32E-44 | 6.57E-42 |
gene expression | GO:0010467 | 592 | 2567 | 4.26E-44 | 8.21E-42 |
extracellular region | GO:0005576 | 521 | 2150 | 1.83E-43 | 3.43E-41 |
extracellular vesicle | GO:1903561 | 366 | 1269 | 2.41E-43 | 4.41E-41 |
extracellular organelle | GO:0043230 | 366 | 1270 | 2.78E-43 | 4.97E-41 |
extracellular exosome | GO:0070062 | 364 | 1262 | 4.17E-43 | 7.27E-41 |
single-organism metabolic process | GO:0044710 | 507 | 2084 | 1.28E-42 | 2.18E-40 |
intracellular organelle lumen | GO:0070013 | 463 | 1852 | 2.99E-41 | 4.77E-39 |
organelle lumen | GO:0043233 | 463 | 1852 | 2.99E-41 | 4.77E-39 |
membrane-enclosed lumen | GO:0031974 | 463 | 1852 | 2.99E-41 | 4.77E-39 |
cellular component organization | GO:0016043 | 620 | 2812 | 4.41E-41 | 6.88E-39 |
biological regulation | GO:0065007 | 1032 | 5627 | 9.23E-40 | 1.41E-37 |
cellular nitrogen compound biosynthetic process | GO:0044271 | 535 | 2320 | 1.6E-39 | 2.4E-37 |
membrane | GO:0016020 | 910 | 4839 | 1.1E-37 | 1.61E-35 |
organic cyclic compound metabolic process | GO:1901360 | 611 | 2852 | 3.26E-37 | 4.69E-35 |
regulation of biological process | GO:0050789 | 964 | 5256 | 1.54E-36 | 2.17E-34 |
cellular aromatic compound metabolic process | GO:0006725 | 594 | 2772 | 4.13E-36 | 5.71E-34 |
heterocycle metabolic process | GO:0046483 | 587 | 2745 | 1.97E-35 | 2.67E-33 |
cellular macromolecule biosynthetic process | GO:0034645 | 514 | 2316 | 3.53E-34 | 4.71E-32 |
nucleobase-containing compound metabolic process | GO:0006139 | 572 | 2684 | 4.17E-34 | 5.46E-32 |
organonitrogen compound biosynthetic process | GO:1901566 | 242 | 763 | 9.85E-34 | 1.27E-31 |
macromolecule biosynthetic process | GO:0009059 | 521 | 2376 | 1.59E-33 | 2.01E-31 |
mitochondrion | GO:0005739 | 296 | 1054 | 2.97E-33 | 3.69E-31 |
regulation of cellular process | GO:0050794 | 910 | 4998 | 4.87E-33 | 5.95E-31 |
protein complex | GO:0043234 | 487 | 2205 | 7.42E-32 | 8.91E-30 |
ion binding | GO:0043167 | 458 | 2028 | 9.53E-32 | 1.13E-29 |
ribonucleoprotein complex | GO:1990904 | 180 | 487 | 1.06E-31 | 1.21E-29 |
intracellular ribonucleoprotein complex | GO:0030529 | 180 | 487 | 1.06E-31 | 1.21E-29 |
metal ion binding | GO:0046872 | 440 | 1919 | 1.08E-31 | 1.21E-29 |
cation binding | GO:0043169 | 442 | 1944 | 3.78E-31 | 4.19E-29 |
organic cyclic compound binding | GO:0097159 | 625 | 3117 | 5.9E-31 | 6.46E-29 |
heterocyclic compound binding | GO:1901363 | 618 | 3076 | 8.82E-31 | 9.5E-29 |
regulation of metabolic process | GO:0019222 | 573 | 2794 | 2.43E-30 | 2.58E-28 |
non-membrane-bounded organelle | GO:0043228 | 449 | 2014 | 4.93E-30 | 5.09E-28 |
intracellular non-membrane-bounded organelle | GO:0043232 | 449 | 2014 | 4.93E-30 | 5.09E-28 |
cellular amide metabolic process | GO:0043603 | 187 | 546 | 1.57E-29 | 1.6E-27 |
nuclear part | GO:0044428 | 414 | 1817 | 2.79E-29 | 2.8E-27 |
mitochondrial part | GO:0044429 | 191 | 578 | 1.47E-28 | 1.46E-26 |
regulation of cellular metabolic process | GO:0031323 | 543 | 2671 | 7.56E-28 | 7.38E-26 |
organelle organization | GO:0006996 | 407 | 1810 | 8.73E-28 | 8.42E-26 |
amide biosynthetic process | GO:0043604 | 165 | 467 | 2.25E-27 | 2.14E-25 |
regulation of primary metabolic process | GO:0080090 | 537 | 2655 | 4.57E-27 | 4.3E-25 |
regulation of macromolecule metabolic process | GO:0060255 | 534 | 2637 | 5.17E-27 | 4.8E-25 |
organelle membrane | GO:0031090 | 302 | 1203 | 6.29E-27 | 5.76E-25 |
peptide metabolic process | GO:0006518 | 167 | 484 | 9.15E-27 | 8.28E-25 |
response to stimulus | GO:0050896 | 715 | 3881 | 3.01E-26 | 2.69E-24 |
peptide biosynthetic process | GO:0043043 | 154 | 432 | 6.03E-26 | 5.32E-24 |
protein binding | GO:0005515 | 572 | 2939 | 2.27E-25 | 1.98E-23 |
translation | GO:0006412 | 150 | 422 | 3.36E-25 | 2.9E-23 |
nucleic acid metabolic process | GO:0090304 | 484 | 2370 | 4.79E-25 | 4.08E-23 |
RNA binding | GO:0003723 | 236 | 874 | 1.21E-24 | 1.02E-22 |
nuclear lumen | GO:0031981 | 354 | 1571 | 2.87E-24 | 2.39E-22 |
ribosome | GO:0005840 | 95 | 192 | 3.54E-24 | 2.91E-22 |
mitochondrion organization | GO:0007005 | 144 | 412 | 1.14E-23 | 9.3E-22 |
organelle inner membrane | GO:0019866 | 135 | 370 | 1.23E-23 | 9.93E-22 |
mitochondrial envelope | GO:0005740 | 155 | 468 | 1.88E-23 | 1.5E-21 |
mitochondrial inner membrane | GO:0005743 | 130 | 350 | 2.33E-23 | 1.84E-21 |
mitochondrial membrane | GO:0031966 | 149 | 445 | 5.8E-23 | 4.52E-21 |
RNA metabolic process | GO:0016070 | 435 | 2120 | 8.75E-23 | 6.75E-21 |
catabolic process | GO:0009056 | 225 | 848 | 1.02E-22 | 7.69E-21 |
macromolecule modification | GO:0043412 | 401 | 1911 | 1.74E-22 | 1.3E-20 |
envelope | GO:0031975 | 186 | 642 | 2.22E-22 | 1.64E-20 |
organelle envelope | GO:0031967 | 185 | 641 | 4.11E-22 | 3.01E-20 |
cytosol | GO:0005829 | 230 | 888 | 4.44E-22 | 3.22E-20 |
protein modification process | GO:0036211 | 383 | 1819 | 1.08E-21 | 7.68E-20 |
cellular protein modification process | GO:0006464 | 383 | 1819 | 1.08E-21 | 7.68E-20 |
positive regulation of biological process | GO:0048518 | 466 | 2358 | 1.32E-21 | 9.32E-20 |
oxidation-reduction process | GO:0055114 | 182 | 637 | 2.23E-21 | 1.56E-19 |
organic substance catabolic process | GO:1901575 | 216 | 825 | 2.94E-21 | 2.01E-19 |
hydrolase activity | GO:0016787 | 301 | 1325 | 4.05E-21 | 2.75E-19 |
nucleic acid binding | GO:0003676 | 409 | 2004 | 4.79E-21 | 3.22E-19 |
small molecule metabolic process | GO:0044281 | 237 | 950 | 5.82E-21 | 3.87E-19 |
ribosomal subunit | GO:0044391 | 75 | 142 | 1.23E-20 | 8.11E-19 |
single-multicellular organism process | GO:0044707 | 480 | 2497 | 3.33E-20 | 2.18E-18 |
structural constituent of ribosome | GO:0003735 | 86 | 189 | 3.36E-20 | 2.18E-18 |
organic cyclic compound biosynthetic process | GO:1901362 | 397 | 1960 | 6.15E-20 | 3.95E-18 |
nucleoplasm | GO:0005654 | 261 | 1113 | 6.41E-20 | 4.08E-18 |
positive regulation of cellular process | GO:0048522 | 426 | 2156 | 1.03E-19 | 6.54E-18 |
aromatic compound biosynthetic process | GO:0019438 | 387 | 1903 | 1.09E-19 | 6.8E-18 |
endomembrane system | GO:0012505 | 360 | 1730 | 1.1E-19 | 6.8E-18 |
cellular response to stimulus | GO:0051716 | 588 | 3259 | 1.84E-19 | 1.14E-17 |
structural molecule activity | GO:0005198 | 129 | 394 | 2.19E-19 | 1.33E-17 |
regulation of response to stimulus | GO:0048583 | 328 | 1552 | 8.07E-19 | 4.87E-17 |
regulation of gene expression | GO:0010468 | 377 | 1865 | 8.11E-19 | 4.87E-17 |
heterocycle biosynthetic process | GO:0018130 | 381 | 1895 | 1.1E-18 | 6.56E-17 |
localization | GO:0051179 | 512 | 2770 | 1.32E-18 | 7.82E-17 |
nucleobase-containing compound biosynthetic process | GO:0034654 | 374 | 1854 | 1.52E-18 | 8.9E-17 |
regulation of biosynthetic process | GO:0009889 | 378 | 1883 | 1.91E-18 | 1.11E-16 |
proteolysis | GO:0006508 | 205 | 820 | 2.42E-18 | 1.4E-16 |
phosphorus metabolic process | GO:0006793 | 317 | 1500 | 3.33E-18 | 1.91E-16 |
phosphate-containing compound metabolic process | GO:0006796 | 316 | 1496 | 4.02E-18 | 2.28E-16 |
negative regulation of biological process | GO:0048519 | 400 | 2040 | 4.95E-18 | 2.79E-16 |
regulation of cellular biosynthetic process | GO:0031326 | 371 | 1855 | 6.85E-18 | 3.83E-16 |
cellular catabolic process | GO:0044248 | 180 | 688 | 7.31E-18 | 4.06E-16 |
regulation of protein metabolic process | GO:0051246 | 268 | 1209 | 1.06E-17 | 5.86E-16 |
mitochondrial matrix | GO:0005759 | 83 | 200 | 1.2E-17 | 6.58E-16 |
negative regulation of cellular process | GO:0048523 | 377 | 1904 | 1.4E-17 | 7.6E-16 |
regulation of nitrogen compound metabolic process | GO:0051171 | 376 | 1907 | 2.75E-17 | 1.48E-15 |
single-organism developmental process | GO:0044767 | 462 | 2483 | 3.36E-17 | 1.8E-15 |
regulation of cellular macromolecule biosynthetic process | GO:2000112 | 349 | 1736 | 3.87E-17 | 2.06E-15 |
developmental process | GO:0032502 | 464 | 2503 | 4.99E-17 | 2.63E-15 |
regulation of cellular protein metabolic process | GO:0032268 | 254 | 1145 | 7.49E-17 | 3.92E-15 |
regulation of macromolecule biosynthetic process | GO:0010556 | 355 | 1786 | 8.63E-17 | 4.49E-15 |
membrane part | GO:0044425 | 629 | 3668 | 1.34E-16 | 6.91E-15 |
membrane protein complex | GO:0098796 | 163 | 619 | 1.68E-16 | 8.61E-15 |
single-organism biosynthetic process | GO:0044711 | 167 | 650 | 4.73E-16 | 2.41E-14 |
poly(A) RNA binding | GO:0044822 | 155 | 585 | 6.03E-16 | 3.05E-14 |
response to stress | GO:0006950 | 310 | 1525 | 7.76E-16 | 3.89E-14 |
anatomical structure development | GO:0048856 | 429 | 2316 | 1.06E-15 | 5.3E-14 |
transport | GO:0006810 | 410 | 2189 | 1.15E-15 | 5.67E-14 |
cellular component biogenesis | GO:0044085 | 269 | 1270 | 1.17E-15 | 5.75E-14 |
mitochondrial membrane part | GO:0044455 | 65 | 145 | 2.22E-15 | 1.09E-13 |
establishment of localization | GO:0051234 | 419 | 2261 | 2.29E-15 | 1.11E-13 |
carbohydrate derivative metabolic process | GO:1901135 | 149 | 563 | 2.42E-15 | 1.16E-13 |
regulation of molecular function | GO:0065009 | 262 | 1235 | 2.42E-15 | 1.16E-13 |
oxidoreductase activity | GO:0016491 | 139 | 509 | 2.71E-15 | 1.29E-13 |
multicellular organism development | GO:0007275 | 381 | 2020 | 5.69E-15 | 2.69E-13 |
positive regulation of metabolic process | GO:0009893 | 283 | 1379 | 5.88E-15 | 2.76E-13 |
translational initiation | GO:0006413 | 64 | 146 | 8.29E-15 | 3.87E-13 |
translational elongation | GO:0006414 | 54 | 106 | 9.02E-15 | 4.18E-13 |
mitochondrial protein complex | GO:0098798 | 57 | 118 | 9.7E-15 | 4.47E-13 |
ribonucleoprotein complex biogenesis | GO:0022613 | 88 | 255 | 9.86E-15 | 4.52E-13 |
catalytic complex | GO:1902494 | 158 | 627 | 1.19E-14 | 5.42E-13 |
regulation of catalytic activity | GO:0050790 | 220 | 994 | 1.22E-14 | 5.52E-13 |
inner mitochondrial membrane protein complex | GO:0098800 | 52 | 101 | 2.03E-14 | 9.12E-13 |
small molecule binding | GO:0036094 | 280 | 1379 | 2.49E-14 | 1.11E-12 |
positive regulation of cellular metabolic process | GO:0031325 | 269 | 1312 | 3.2E-14 | 1.42E-12 |
mitochondrial translation | GO:0032543 | 51 | 99 | 3.54E-14 | 1.56E-12 |
regulation of nucleobase-containing compound metabolic process | GO:0019219 | 340 | 1777 | 3.91E-14 | 1.72E-12 |
organic substance transport | GO:0071702 | 243 | 1156 | 6.27E-14 | 2.73E-12 |
mitochondrial translational elongation | GO:0070125 | 44 | 75 | 6.67E-14 | 2.89E-12 |
macromolecule localization | GO:0033036 | 251 | 1208 | 7.09E-14 | 3.06E-12 |
regulation of signal transduction | GO:0009966 | 247 | 1184 | 7.84E-14 | 3.36E-12 |
macromolecule catabolic process | GO:0009057 | 134 | 514 | 1.59E-13 | 6.77E-12 |
transferase activity | GO:0016740 | 259 | 1270 | 1.66E-13 | 7.04E-12 |
positive regulation of macromolecule metabolic process | GO:0010604 | 262 | 1292 | 2.05E-13 | 8.63E-12 |
nucleotide binding | GO:0000166 | 261 | 1289 | 2.64E-13 | 1.1E-11 |
nucleoside phosphate binding | GO:1901265 | 261 | 1289 | 2.64E-13 | 1.1E-11 |
mitochondrial translational initiation | GO:0070124 | 43 | 76 | 3.22E-13 | 1.33E-11 |
RNA biosynthetic process | GO:0032774 | 315 | 1648 | 4.21E-13 | 1.73E-11 |
mitochondrial ribosome | GO:0005761 | 39 | 63 | 4.98E-13 | 2.03E-11 |
organellar ribosome | GO:0000313 | 39 | 63 | 4.98E-13 | 2.03E-11 |
macromolecular complex subunit organization | GO:0043933 | 225 | 1069 | 5.04E-13 | 2.04E-11 |
regulation of signaling | GO:0023051 | 262 | 1305 | 5.3E-13 | 2.13E-11 |
system development | GO:0048731 | 337 | 1799 | 5.57E-13 | 2.23E-11 |
transcription, DNA-templated | GO:0006351 | 310 | 1620 | 5.85E-13 | 2.33E-11 |
regulation of cell communication | GO:0010646 | 260 | 1294 | 6.07E-13 | 2.41E-11 |
multicellular organismal process | GO:0032501 | 520 | 3067 | 6.36E-13 | 2.5E-11 |
nucleic acid-templated transcription | GO:0097659 | 311 | 1635 | 1E-12 | 3.92E-11 |
nucleobase-containing small molecule metabolic process | GO:0055086 | 100 | 345 | 1.21E-12 | 4.71E-11 |
endoplasmic reticulum | GO:0005783 | 167 | 724 | 1.26E-12 | 4.87E-11 |
RNA processing | GO:0006396 | 117 | 443 | 2.74E-12 | 1.06E-10 |
large ribosomal subunit | GO:0015934 | 43 | 83 | 3.02E-12 | 1.16E-10 |
nucleoside phosphate metabolic process | GO:0006753 | 94 | 320 | 3.06E-12 | 1.17E-10 |
intracellular signal transduction | GO:0035556 | 238 | 1175 | 3.08E-12 | 1.17E-10 |
cytosolic ribosome | GO:0022626 | 46 | 95 | 3.3E-12 | 1.25E-10 |
regulation of biological quality | GO:0065008 | 290 | 1518 | 4.13E-12 | 1.55E-10 |
respiratory chain complex I | GO:0045271 | 32 | 45 | 4.27E-12 | 1.58E-10 |
mitochondrial respiratory chain complex I | GO:0005747 | 32 | 45 | 4.27E-12 | 1.58E-10 |
NADH dehydrogenase complex | GO:0030964 | 32 | 45 | 4.27E-12 | 1.58E-10 |
positive regulation of response to stimulus | GO:0048584 | 185 | 848 | 4.92E-12 | 1.81E-10 |
regulation of transcription, DNA-templated | GO:0006355 | 295 | 1555 | 5.28E-12 | 1.94E-10 |
cellular macromolecule catabolic process | GO:0044265 | 113 | 427 | 5.81E-12 | 2.12E-10 |
regulation of RNA biosynthetic process | GO:2001141 | 298 | 1577 | 6.01E-12 | 2.18E-10 |
regulation of nucleic acid-templated transcription | GO:1903506 | 297 | 1573 | 7.1E-12 | 2.56E-10 |
phosphorylation | GO:0016310 | 221 | 1078 | 7.24E-12 | 2.6E-10 |
cellular developmental process | GO:0048869 | 328 | 1784 | 8.54E-12 | 3.05E-10 |
nucleotide metabolic process | GO:0009117 | 92 | 317 | 9E-12 | 3.2E-10 |
animal organ development | GO:0048513 | 260 | 1333 | 9.27E-12 | 3.28E-10 |
regulation of RNA metabolic process | GO:0051252 | 305 | 1632 | 1E-11 | 3.53E-10 |
cellular response to stress | GO:0033554 | 173 | 790 | 1.9E-11 | 6.63E-10 |
peptidase activity | GO:0008233 | 91 | 317 | 1.9E-11 | 6.63E-10 |
cell differentiation | GO:0030154 | 301 | 1616 | 1.92E-11 | 6.68E-10 |
purine-containing compound metabolic process | GO:0072521 | 82 | 273 | 2.93E-11 | 0.000000001 |
ribosome biogenesis | GO:0042254 | 61 | 171 | 3.92E-11 | 1.35E-09 |
ribose phosphate metabolic process | GO:0019693 | 79 | 260 | 4.24E-11 | 1.45E-09 |
organophosphate metabolic process | GO:0019637 | 120 | 484 | 4.51E-11 | 1.54E-09 |
positive regulation of signal transduction | GO:0009967 | 144 | 629 | 7.12E-11 | 2.41E-09 |
cellular protein localization | GO:0034613 | 156 | 704 | 9.05E-11 | 3.06E-09 |
cellular component assembly | GO:0022607 | 224 | 1135 | 1.11E-10 | 3.71E-09 |
single-organism organelle organization | GO:1902589 | 177 | 836 | 1.13E-10 | 3.77E-09 |
intracellular transport | GO:0046907 | 146 | 646 | 1.14E-10 | 3.78E-09 |
peptidase activity, acting on L-amino acid peptides | GO:0070011 | 87 | 309 | 1.19E-10 | 0.000000004 |
extracellular space | GO:0005615 | 144 | 635 | 1.25E-10 | 4.12E-09 |
cell communication | GO:0007154 | 478 | 2885 | 1.33E-10 | 4.36E-09 |
cellular macromolecule localization | GO:0070727 | 156 | 709 | 1.41E-10 | 4.6E-09 |
carbohydrate derivative binding | GO:0097367 | 226 | 1152 | 1.46E-10 | 4.74E-09 |
regulation of hydrolase activity | GO:0051336 | 132 | 566 | 1.59E-10 | 5.16E-09 |
purine nucleotide metabolic process | GO:0006163 | 76 | 254 | 1.77E-10 | 5.72E-09 |
nucleolus | GO:0005730 | 108 | 429 | 2E-10 | 6.44E-09 |
protein localization | GO:0008104 | 209 | 1047 | 2.06E-10 | 6.6E-09 |
cellular localization | GO:0051641 | 208 | 1041 | 2.13E-10 | 6.78E-09 |
single-organism catabolic process | GO:0044712 | 96 | 363 | 2.31E-10 | 7.32E-09 |
regulation of multicellular organismal process | GO:0051239 | 218 | 1108 | 2.51E-10 | 7.92E-09 |
signal transduction | GO:0007165 | 447 | 2682 | 2.97E-10 | 9.34E-09 |
cell death | GO:0008219 | 174 | 831 | 3.37E-10 | 1.06E-08 |
signaling | GO:0023052 | 470 | 2850 | 3.47E-10 | 1.08E-08 |
purine nucleoside metabolic process | GO:0042278 | 60 | 178 | 3.49E-10 | 1.08E-08 |
establishment of protein localization | GO:0045184 | 177 | 851 | 3.69E-10 | 1.14E-08 |
ribonucleotide metabolic process | GO:0009259 | 75 | 254 | 3.83E-10 | 1.18E-08 |
single organism signaling | GO:0044700 | 469 | 2847 | 4.15E-10 | 1.27E-08 |
purine ribonucleotide metabolic process | GO:0009150 | 73 | 246 | 5.44E-10 | 1.66E-08 |
cytosolic part | GO:0044445 | 58 | 171 | 5.63E-10 | 1.71E-08 |
protein catabolic process | GO:0030163 | 100 | 393 | 5.75E-10 | 1.74E-08 |
calcium ion binding | GO:0005509 | 91 | 343 | 5.88E-10 | 1.77E-08 |
programmed cell death | GO:0012501 | 166 | 788 | 5.92E-10 | 1.78E-08 |
nucleoside metabolic process | GO:0009116 | 63 | 196 | 6.16E-10 | 1.84E-08 |
positive regulation of cell communication | GO:0010647 | 149 | 684 | 6.59E-10 | 1.96E-08 |
nucleoside triphosphate metabolic process | GO:0009141 | 54 | 153 | 6.88E-10 | 2.04E-08 |
small ribosomal subunit | GO:0015935 | 32 | 59 | 7.36E-10 | 2.17E-08 |
single-organism localization | GO:1902578 | 246 | 1310 | 7.95E-10 | 2.34E-08 |
positive regulation of signaling | GO:0023056 | 149 | 687 | 8.51E-10 | 2.49E-08 |
transition metal ion binding | GO:0046914 | 161 | 763 | 0.000000001 | 2.83E-08 |
intracellular protein transport | GO:0006886 | 110 | 455 | 0.000000001 | 2.83E-08 |
purine ribonucleoside metabolic process | GO:0046128 | 58 | 175 | 1.14E-09 | 3.31E-08 |
molecular function regulator | GO:0098772 | 134 | 599 | 1.15E-09 | 3.33E-08 |
Golgi apparatus | GO:0005794 | 138 | 624 | 1.23E-09 | 3.54E-08 |
proteolysis involved in cellular protein catabolic process | GO:0051603 | 87 | 327 | 1.24E-09 | 3.55E-08 |
regulation of cellular component organization | GO:0051128 | 200 | 1016 | 1.37E-09 | 0.000000039 |
negative regulation of metabolic process | GO:0009892 | 213 | 1101 | 1.4E-09 | 3.96E-08 |
negative regulation of cellular metabolic process | GO:0031324 | 204 | 1043 | 1.47E-09 | 4.15E-08 |
cellular protein catabolic process | GO:0044257 | 89 | 340 | 1.58E-09 | 4.44E-08 |
negative regulation of response to stimulus | GO:0048585 | 134 | 603 | 1.65E-09 | 4.64E-08 |
glycosyl compound metabolic process | GO:1901657 | 63 | 203 | 1.93E-09 | 5.38E-08 |
extracellular matrix | GO:0031012 | 59 | 183 | 1.94E-09 | 5.38E-08 |
apoptotic process | GO:0006915 | 162 | 778 | 1.94E-09 | 5.38E-08 |
mitochondrial respiratory chain | GO:0005746 | 33 | 67 | 2.61E-09 | 0.000000072 |
ribonucleoside metabolic process | GO:0009119 | 60 | 190 | 2.7E-09 | 7.45E-08 |
protein transport | GO:0015031 | 162 | 783 | 2.85E-09 | 7.83E-08 |
purine nucleotide binding | GO:0017076 | 197 | 1008 | 0.000000003 | 8.15E-08 |
positive regulation of protein metabolic process | GO:0051247 | 144 | 672 | 3.21E-09 | 8.73E-08 |
oxidoreductase complex | GO:1990204 | 36 | 80 | 3.32E-09 | 0.00000009 |
organic acid metabolic process | GO:0006082 | 110 | 468 | 3.68E-09 | 9.95E-08 |
macromolecular complex assembly | GO:0065003 | 156 | 749 | 3.82E-09 | 0.000000103 |
negative regulation of signal transduction | GO:0009968 | 112 | 481 | 4.15E-09 | 0.000000111 |
regulation of cell death | GO:0010941 | 138 | 639 | 4.49E-09 | 0.00000012 |
regulation of intracellular signal transduction | GO:1902531 | 153 | 733 | 4.76E-09 | 0.000000127 |
positive regulation of molecular function | GO:0044093 | 148 | 702 | 4.87E-09 | 0.000000129 |
purine ribonucleotide binding | GO:0032555 | 195 | 1003 | 5.09E-09 | 0.000000135 |
purine ribonucleoside binding | GO:0032550 | 192 | 985 | 5.65E-09 | 0.000000149 |
ribonucleotide binding | GO:0032553 | 196 | 1012 | 0.000000006 | 0.000000157 |
purine nucleoside binding | GO:0001883 | 192 | 986 | 0.000000006 | 0.000000158 |
regulation of phosphorus metabolic process | GO:0051174 | 159 | 774 | 6.08E-09 | 0.000000158 |
regulation of phosphate metabolic process | GO:0019220 | 159 | 774 | 6.08E-09 | 0.000000158 |
positive regulation of cellular protein metabolic process | GO:0032270 | 137 | 637 | 6.36E-09 | 0.000000164 |
response to oxidative stress | GO:0006979 | 50 | 146 | 6.5E-09 | 0.000000167 |
ribonucleoside binding | GO:0032549 | 192 | 988 | 6.9E-09 | 0.000000177 |
regulation of programmed cell death | GO:0043067 | 132 | 608 | 7.4E-09 | 0.000000188 |
single-organism transport | GO:0044765 | 226 | 1215 | 0.000000008 | 0.000000203 |
nucleoside binding | GO:0001882 | 192 | 991 | 8.41E-09 | 0.000000212 |
bounding membrane of organelle | GO:0098588 | 148 | 709 | 8.46E-09 | 0.000000213 |
establishment of localization in cell | GO:0051649 | 163 | 806 | 9.89E-09 | 0.000000248 |
purine ribonucleoside triphosphate binding | GO:0035639 | 190 | 981 | 1.03E-08 | 0.000000257 |
ribonucleoprotein complex assembly | GO:0022618 | 46 | 130 | 1.14E-08 | 0.000000285 |
regulation of apoptotic process | GO:0042981 | 130 | 602 | 1.26E-08 | 0.000000313 |
cofactor metabolic process | GO:0051186 | 59 | 195 | 1.33E-08 | 0.000000328 |
single-organism cellular localization | GO:1902580 | 106 | 458 | 0.000000014 | 0.000000346 |
intrinsic component of membrane | GO:0031224 | 495 | 3125 | 1.45E-08 | 0.000000358 |
ribonucleoprotein complex subunit organization | GO:0071826 | 47 | 137 | 1.74E-08 | 0.000000426 |
carbohydrate metabolic process | GO:0005975 | 93 | 384 | 1.75E-08 | 0.000000426 |
respiratory chain complex | GO:0098803 | 33 | 74 | 1.75E-08 | 0.000000426 |
cytoplasmic vesicle | GO:0031410 | 117 | 527 | 1.85E-08 | 0.000000449 |
cytoskeleton | GO:0005856 | 182 | 939 | 2.02E-08 | 0.000000488 |
intracellular vesicle | GO:0097708 | 117 | 528 | 2.02E-08 | 0.000000488 |
purine nucleoside triphosphate metabolic process | GO:0009144 | 47 | 138 | 2.09E-08 | 0.000000503 |
small molecule biosynthetic process | GO:0044283 | 69 | 251 | 2.11E-08 | 0.000000505 |
negative regulation of cell communication | GO:0010648 | 114 | 511 | 2.25E-08 | 0.000000535 |
cellular response to chemical stimulus | GO:0070887 | 199 | 1053 | 2.32E-08 | 0.000000551 |
vacuole | GO:0005773 | 117 | 530 | 2.41E-08 | 0.000000571 |
negative regulation of signaling | GO:0023057 | 114 | 512 | 2.46E-08 | 0.000000579 |
negative regulation of macromolecule metabolic process | GO:0010605 | 194 | 1022 | 2.64E-08 | 0.00000062 |
carbohydrate derivative biosynthetic process | GO:1901137 | 85 | 342 | 2.68E-08 | 0.000000628 |
ncRNA metabolic process | GO:0034660 | 71 | 264 | 2.77E-08 | 0.000000647 |
ribonucleoside triphosphate metabolic process | GO:0009199 | 47 | 140 | 0.00000003 | 0.000000698 |
integral component of membrane | GO:0016021 | 485 | 3079 | 3.93E-08 | 0.000000907 |
endoplasmic reticulum part | GO:0044432 | 104 | 458 | 4.34E-08 | 0.000001 |
positive regulation of catalytic activity | GO:0043085 | 123 | 574 | 4.46E-08 | 0.00000102 |
regulation of protein modification process | GO:0031399 | 155 | 776 | 4.52E-08 | 0.00000103 |
anatomical structure morphogenesis | GO:0009653 | 212 | 1151 | 4.58E-08 | 0.00000104 |
nuclear outer membrane-endoplasmic reticulum membrane network | GO:0042175 | 97 | 417 | 4.63E-08 | 0.00000105 |
protein phosphorylation | GO:0006468 | 171 | 880 | 4.68E-08 | 0.00000106 |
nucleoplasm part | GO:0044451 | 90 | 377 | 5.17E-08 | 0.00000116 |
regulation of phosphorylation | GO:0042325 | 138 | 670 | 5.34E-08 | 0.0000012 |
zinc ion binding | GO:0008270 | 126 | 595 | 5.43E-08 | 0.00000122 |
lysosome | GO:0005764 | 62 | 221 | 5.83E-08 | 0.0000013 |
lytic vacuole | GO:0000323 | 62 | 221 | 5.83E-08 | 0.0000013 |
carboxylic acid metabolic process | GO:0019752 | 97 | 420 | 6.19E-08 | 0.00000137 |
tissue development | GO:0009888 | 153 | 768 | 6.37E-08 | 0.000001409 |
regulation of developmental process | GO:0050793 | 186 | 984 | 6.65E-08 | 0.000001467 |
oxoacid metabolic process | GO:0043436 | 97 | 421 | 6.81E-08 | 0.000001499 |
purine ribonucleoside triphosphate metabolic process | GO:0009205 | 45 | 135 | 6.92E-08 | 0.00000152 |
transcription from RNA polymerase II promoter | GO:0006366 | 176 | 919 | 7.04E-08 | 0.00000154 |
cellular component disassembly | GO:0022411 | 60 | 212 | 7.33E-08 | 0.0000016 |
response to organic substance | GO:0010033 | 201 | 1086 | 7.59E-08 | 0.00000165 |
mRNA metabolic process | GO:0016071 | 71 | 273 | 8.41E-08 | 0.00000182 |
cellular macromolecular complex assembly | GO:0034622 | 109 | 496 | 8.76E-08 | 0.00000189 |
cell cycle | GO:0007049 | 141 | 696 | 8.97E-08 | 0.00000193 |
ncRNA processing | GO:0034470 | 58 | 203 | 9.16E-08 | 0.00000197 |
nucleoside monophosphate metabolic process | GO:0009123 | 50 | 162 | 9.86E-08 | 0.00000211 |
purine ribonucleoside biosynthetic process | GO:0046129 | 27 | 56 | 9.93E-08 | 0.000002114 |
purine nucleoside biosynthetic process | GO:0042451 | 27 | 56 | 9.93E-08 | 0.000002114 |
organophosphate biosynthetic process | GO:0090407 | 66 | 247 | 0.000000103 | 0.00000218 |
endopeptidase activity | GO:0004175 | 60 | 215 | 0.00000011 | 0.00000233 |
protein targeting | GO:0006605 | 73 | 287 | 0.000000117 | 0.00000247 |
endoplasmic reticulum membrane | GO:0005789 | 94 | 409 | 0.000000119 | 0.0000025 |
enzyme regulator activity | GO:0030234 | 102 | 457 | 0.000000119 | 0.0000025 |
negative regulation of protein metabolic process | GO:0051248 | 106 | 482 | 0.000000127 | 0.00000266 |
cell proliferation | GO:0008283 | 161 | 830 | 0.000000127 | 0.00000266 |
negative regulation of cellular protein metabolic process | GO:0032269 | 103 | 464 | 0.00000013 | 0.000002702 |
cell surface receptor signaling pathway | GO:0007166 | 203 | 1113 | 0.000000165 | 0.00000343 |
cytoplasmic, membrane-bounded vesicle | GO:0016023 | 105 | 479 | 0.000000167 | 0.00000345 |
peptidyl-amino acid modification | GO:0018193 | 118 | 560 | 0.000000178 | 0.000003671 |
establishment of protein localization to organelle | GO:0072594 | 68 | 263 | 0.000000187 | 0.00000386 |
organonitrogen compound catabolic process | GO:1901565 | 41 | 122 | 0.000000217 | 0.00000445 |
transferase complex | GO:1990234 | 91 | 398 | 0.000000229 | 0.00000468 |
regulation of protein phosphorylation | GO:0001932 | 127 | 620 | 0.000000232 | 0.00000474 |
respiratory chain | GO:0070469 | 33 | 85 | 0.000000235 | 0.00000478 |
negative regulation of intracellular signal transduction | GO:1902532 | 59 | 216 | 0.000000257 | 0.00000522 |
purine ribonucleoside monophosphate metabolic process | GO:0009167 | 46 | 148 | 0.000000266 | 0.00000539 |
positive regulation of intracellular signal transduction | GO:1902533 | 94 | 418 | 0.000000276 | 0.00000557 |
cytosolic large ribosomal subunit | GO:0022625 | 25 | 52 | 0.000000305 | 0.00000613 |
purine nucleoside monophosphate metabolic process | GO:0009126 | 46 | 149 | 0.000000312 | 0.00000627 |
RNA splicing | GO:0008380 | 54 | 191 | 0.00000033 | 0.00000661 |
regulation of organelle organization | GO:0033043 | 110 | 518 | 0.000000332 | 0.00000663 |
nucleoside biosynthetic process | GO:0009163 | 29 | 69 | 0.000000336 | 0.00000668 |
ribonucleoside biosynthetic process | GO:0042455 | 29 | 69 | 0.000000336 | 0.00000668 |
ribonucleoside monophosphate metabolic process | GO:0009161 | 47 | 155 | 0.000000359 | 0.00000711 |
hydrolase activity, acting on ester bonds | GO:0016788 | 91 | 403 | 0.000000364 | 0.0000072 |
positive regulation of biosynthetic process | GO:0009891 | 155 | 807 | 0.000000365 | 0.0000072 |
generation of precursor metabolites and energy | GO:0006091 | 54 | 192 | 0.000000378 | 0.00000743 |
proteasome complex | GO:0000502 | 25 | 53 | 0.000000402 | 0.00000786 |
nucleoside phosphate biosynthetic process | GO:1901293 | 48 | 161 | 0.000000409 | 0.00000797 |
whole membrane | GO:0098805 | 121 | 590 | 0.000000422 | 0.0000082 |
regulation of proteolysis | GO:0030162 | 77 | 322 | 0.000000436 | 0.00000845 |
adenyl nucleotide binding | GO:0030554 | 144 | 739 | 0.000000468 | 0.00000904 |
posttranscriptional regulation of gene expression | GO:0010608 | 52 | 183 | 0.000000475 | 0.000009153 |
regulation of translation | GO:0006417 | 47 | 157 | 0.000000487 | 0.00000937 |
positive regulation of gene expression | GO:0010628 | 148 | 766 | 0.000000498 | 0.00000955 |
regulation of transcription from RNA polymerase II promoter | GO:0006357 | 166 | 885 | 0.000000514 | 0.00000983 |
ATP metabolic process | GO:0046034 | 41 | 127 | 0.000000516 | 0.00000985 |
glycosyl compound biosynthetic process | GO:1901659 | 29 | 71 | 0.000000539 | 0.0000103 |
adenyl ribonucleotide binding | GO:0032559 | 143 | 735 | 0.000000552 | 0.0000105 |
negative regulation of molecular function | GO:0044092 | 106 | 500 | 0.000000577 | 0.0000109 |
positive regulation of nitrogen compound metabolic process | GO:0051173 | 154 | 808 | 0.000000591 | 0.0000112 |
mRNA processing | GO:0006397 | 59 | 223 | 0.000000625 | 0.0000118 |
negative regulation of catalytic activity | GO:0043086 | 85 | 373 | 0.000000633 | 0.0000119 |
regulation of cellular amide metabolic process | GO:0034248 | 48 | 164 | 0.000000637 | 0.0000119 |
organic acid biosynthetic process | GO:0016053 | 47 | 159 | 0.000000657 | 0.0000123 |
positive regulation of phosphate metabolic process | GO:0045937 | 104 | 490 | 0.000000702 | 0.000013 |
positive regulation of phosphorus metabolic process | GO:0010562 | 104 | 490 | 0.000000702 | 0.000013 |
nucleoside triphosphate biosynthetic process | GO:0009142 | 23 | 47 | 0.000000706 | 0.0000131 |
single-organism carbohydrate metabolic process | GO:0044723 | 75 | 316 | 0.000000779 | 0.0000144 |
ATP binding | GO:0005524 | 140 | 721 | 0.000000796 | 0.0000147 |
positive regulation of nucleobase-containing compound metabolic process | GO:0045935 | 147 | 768 | 0.000000863 | 0.0000159 |
NADH dehydrogenase activity | GO:0003954 | 18 | 29 | 0.000000888 | 0.0000163 |
positive regulation of cellular biosynthetic process | GO:0031328 | 150 | 790 | 0.000000996 | 0.0000182 |
single-organism membrane organization | GO:0044802 | 81 | 355 | 0.0000011 | 0.0000201 |
single-organism intracellular transport | GO:1902582 | 70 | 291 | 0.00000119 | 0.0000217 |
mitochondrial large ribosomal subunit | GO:0005762 | 18 | 30 | 0.00000128 | 0.0000232 |
organellar large ribosomal subunit | GO:0000315 | 18 | 30 | 0.00000128 | 0.0000232 |
coenzyme metabolic process | GO:0006732 | 44 | 148 | 0.00000129 | 0.0000234 |
NADH dehydrogenase (quinone) activity | GO:0050136 | 17 | 27 | 0.00000154 | 0.000027688 |
NADH dehydrogenase (ubiquinone) activity | GO:0008137 | 17 | 27 | 0.00000154 | 0.000027688 |
organic cyclic compound catabolic process | GO:1901361 | 42 | 139 | 0.00000158 | 0.0000283 |
heterocycle catabolic process | GO:0046700 | 39 | 124 | 0.00000164 | 0.0000294 |
anchoring junction | GO:0070161 | 57 | 221 | 0.00000188 | 0.0000335 |
cellular nitrogen compound catabolic process | GO:0044270 | 39 | 125 | 0.00000193 | 0.0000343 |
protein localization to organelle | GO:0033365 | 83 | 374 | 0.00000209 | 0.000037 |
nucleotide biosynthetic process | GO:0009165 | 45 | 157 | 0.000002237 | 0.0000396 |
mitochondrial transport | GO:0006839 | 39 | 126 | 0.00000227 | 0.00004 |
rRNA metabolic process | GO:0016072 | 36 | 111 | 0.00000228 | 0.00004 |
rRNA processing | GO:0006364 | 36 | 111 | 0.00000228 | 0.00004 |
positive regulation of macromolecule biosynthetic process | GO:0010557 | 140 | 739 | 0.00000252 | 0.0000441 |
cell periphery | GO:0071944 | 348 | 2195 | 0.00000254 | 0.0000444 |
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | GO:0016655 | 18 | 32 | 0.00000255 | 0.0000444 |
immune system process | GO:0002376 | 178 | 995 | 0.00000272 | 0.000047266 |
cytosolic small ribosomal subunit | GO:0022627 | 19 | 36 | 0.00000276 | 0.0000479 |
macromolecular complex binding | GO:0044877 | 113 | 565 | 0.000002794 | 0.0000484 |
cellular response to organic substance | GO:0071310 | 160 | 874 | 0.00000281 | 0.0000486 |
membrane organization | GO:0061024 | 87 | 402 | 0.00000285 | 0.0000492 |
proteinaceous extracellular matrix | GO:0005578 | 41 | 139 | 0.00000344 | 0.0000591 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process | GO:0043281 | 33 | 99 | 0.00000366 | 0.0000627 |
establishment of protein localization to mitochondrion | GO:0072655 | 29 | 80 | 0.00000371 | 0.0000635 |
regulation of cysteine-type endopeptidase activity | GO:2000116 | 34 | 104 | 0.00000372 | 0.0000635 |
regulation of peptidase activity | GO:0052547 | 55 | 216 | 0.0000039 | 0.0000664 |
purine-containing compound biosynthetic process | GO:0072522 | 39 | 130 | 0.00000422 | 0.0000717 |
ribonucleotide biosynthetic process | GO:0009260 | 39 | 131 | 0.0000049 | 0.000083 |
aromatic compound catabolic process | GO:0019439 | 39 | 131 | 0.0000049 | 0.000083 |
purine nucleotide biosynthetic process | GO:0006164 | 38 | 126 | 0.00000502 | 0.0000848 |
protein localization to membrane | GO:0072657 | 48 | 180 | 0.00000555 | 0.0000935 |
ribose phosphate biosynthetic process | GO:0046390 | 39 | 132 | 0.00000569 | 0.0000956 |
nucleoside diphosphate metabolic process | GO:0009132 | 23 | 55 | 0.00000572 | 0.000095945 |
regulation of immune system process | GO:0002682 | 105 | 525 | 0.00000619 | 0.000103587 |
protein targeting to mitochondrion | GO:0006626 | 28 | 78 | 0.0000063 | 0.000105072 |
positive regulation of protein modification process | GO:0031401 | 101 | 500 | 0.00000644 | 0.000107188 |
spliceosomal snRNP complex | GO:0097525 | 21 | 47 | 0.00000647 | 0.000107453 |
protein modification by small protein conjugation or removal | GO:0070647 | 94 | 456 | 0.0000066 | 0.000109422 |
protein localization to mitochondrion | GO:0070585 | 29 | 83 | 0.00000664 | 0.000109877 |
rRNA binding | GO:0019843 | 20 | 43 | 0.00000669 | 0.000110374 |
purine ribonucleotide biosynthetic process | GO:0009152 | 37 | 123 | 0.00000697 | 0.000114813 |
signal transduction by protein phosphorylation | GO:0023014 | 78 | 358 | 0.00000738 | 0.000121025 |
modification-dependent protein catabolic process | GO:0019941 | 65 | 280 | 0.00000755 | 0.000123527 |
positive regulation of phosphorylation | GO:0042327 | 90 | 433 | 0.00000778 | 0.000126982 |
adherens junction | GO:0005912 | 53 | 211 | 0.00000802 | 0.000130588 |
carboxylic acid biosynthetic process | GO:0046394 | 41 | 145 | 0.00000811 | 0.000131803 |
modification-dependent macromolecule catabolic process | GO:0043632 | 66 | 287 | 0.00000838 | 0.000135827 |
response to external stimulus | GO:0009605 | 157 | 874 | 0.0000086 | 0.000139042 |
positive regulation of protein phosphorylation | GO:0001934 | 87 | 416 | 0.00000894 | 0.00014435 |
positive regulation of hydrolase activity | GO:0051345 | 74 | 336 | 0.00000909 | 0.000146412 |
plasma membrane | GO:0005886 | 336 | 2145 | 0.000009489 | 0.00015247 |
cytoskeletal part | GO:0044430 | 132 | 708 | 0.000009552 | 0.000153146 |
organellar small ribosomal subunit | GO:0000314 | 15 | 25 | 0.00000974 | 0.000155479 |
mitochondrial small ribosomal subunit | GO:0005763 | 15 | 25 | 0.00000974 | 0.000155479 |
MAPK cascade | GO:0000165 | 74 | 337 | 0.00000993 | 0.00015809 |
symbiosis, encompassing mutualism through parasitism | GO:0044403 | 66 | 289 | 0.0000101 | 0.000161148 |
negative regulation of cell death | GO:0060548 | 81 | 381 | 0.0000108 | 0.00017112 |
interspecies interaction between organisms | GO:0044419 | 66 | 290 | 0.0000111 | 0.000176332 |
spliceosomal complex | GO:0005681 | 35 | 116 | 0.0000115 | 0.000182219 |
alpha-amino acid metabolic process | GO:1901605 | 34 | 111 | 0.0000118 | 0.00018533 |
identical protein binding | GO:0042802 | 106 | 541 | 0.000012009 | 0.000188819 |
viral process | GO:0016032 | 63 | 273 | 0.0000121 | 0.000189795 |
enzyme binding | GO:0019899 | 137 | 746 | 0.0000125 | 0.000196047 |
Golgi apparatus part | GO:0044431 | 69 | 310 | 0.0000134 | 0.000208566 |
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | GO:0000377 | 39 | 138 | 0.0000134 | 0.000209205 |
mRNA splicing, via spliceosome | GO:0000398 | 39 | 138 | 0.0000134 | 0.000209205 |
small nuclear ribonucleoprotein complex | GO:0030532 | 21 | 50 | 0.0000137 | 0.000212012 |
nucleobase-containing compound catabolic process | GO:0034655 | 34 | 112 | 0.0000137 | 0.000212925 |
regulation of multicellular organismal development | GO:2000026 | 133 | 721 | 0.000013855 | 0.000214167 |
cell-substrate junction | GO:0030055 | 47 | 182 | 0.000014 | 0.000215505 |
nucleoside monophosphate biosynthetic process | GO:0009124 | 23 | 59 | 0.0000143 | 0.000219799 |
regulation of cellular protein localization | GO:1903827 | 54 | 222 | 0.0000143 | 0.000220314 |
regulation of GTPase activity | GO:0043087 | 56 | 234 | 0.000015 | 0.000229631 |
RNA splicing, via transesterification reactions | GO:0000375 | 39 | 139 | 0.0000154 | 0.000236081 |
ribonucleoside triphosphate biosynthetic process | GO:0009201 | 18 | 38 | 0.0000158 | 0.000240612 |
multi-organism cellular process | GO:0044764 | 63 | 276 | 0.0000161 | 0.000245546 |
negative regulation of programmed cell death | GO:0043069 | 77 | 362 | 0.0000173 | 0.000262685 |
nucleotide phosphorylation | GO:0046939 | 21 | 51 | 0.0000173 | 0.000262685 |
purine nucleoside monophosphate biosynthetic process | GO:0009127 | 20 | 47 | 0.00001871 | 0.000282656 |
purine ribonucleoside monophosphate biosynthetic process | GO:0009168 | 20 | 47 | 0.00001871 | 0.000282656 |
focal adhesion | GO:0005925 | 46 | 179 | 0.000019 | 0.000286574 |
vasculature development | GO:0001944 | 66 | 296 | 0.000019374 | 0.000291417 |
regulation of localization | GO:0032879 | 181 | 1055 | 0.0000194 | 0.000291417 |
blood vessel development | GO:0001568 | 64 | 284 | 0.0000195 | 0.000291561 |
positive regulation of RNA biosynthetic process | GO:1902680 | 121 | 648 | 0.0000208 | 0.000311154 |
regulation of MAPK cascade | GO:0043408 | 67 | 303 | 0.0000211 | 0.000314677 |
ubiquitin-dependent protein catabolic process | GO:0006511 | 62 | 273 | 0.0000213 | 0.000317723 |
cell-substrate adherens junction | GO:0005924 | 46 | 180 | 0.0000214 | 0.000317768 |
energy derivation by oxidation of organic compounds | GO:0015980 | 40 | 147 | 0.000021868 | 0.000324346 |
nervous system development | GO:0007399 | 142 | 790 | 0.0000222 | 0.000328648 |
response to oxygen-containing compound | GO:1901700 | 94 | 473 | 0.0000228 | 0.000337535 |
epithelium development | GO:0060429 | 93 | 467 | 0.0000235 | 0.000346864 |
oxidoreductase activity, acting on peroxide as acceptor | GO:0016684 | 14 | 24 | 0.0000243 | 0.000357839 |
oxidoreductase activity, acting on NAD(P)H | GO:0016651 | 22 | 57 | 0.0000246 | 0.000361354 |
microtubule cytoskeleton | GO:0015630 | 106 | 552 | 0.0000248 | 0.000362547 |
regulation of cell proliferation | GO:0042127 | 121 | 651 | 0.0000249 | 0.000362547 |
positive regulation of RNA metabolic process | GO:0051254 | 124 | 671 | 0.0000249 | 0.000362547 |
ribosome assembly | GO:0042255 | 19 | 44 | 0.0000256 | 0.000371934 |
protein complex subunit organization | GO:0071822 | 122 | 659 | 0.0000269 | 0.000389688 |
regulation of protein stability | GO:0031647 | 31 | 101 | 0.0000271 | 0.000391334 |
response to endogenous stimulus | GO:0009719 | 107 | 560 | 0.0000272 | 0.000392677 |
positive regulation of transcription, DNA-templated | GO:0045893 | 120 | 646 | 0.0000274 | 0.000393989 |
positive regulation of nucleic acid-templated transcription | GO:1903508 | 120 | 646 | 0.0000274 | 0.000393989 |
cytoskeleton organization | GO:0007010 | 96 | 489 | 0.0000283 | 0.000406281 |
negative regulation of hydrolase activity | GO:0051346 | 50 | 206 | 0.0000306 | 0.000437689 |
cellular lipid metabolic process | GO:0044255 | 88 | 439 | 0.0000313 | 0.000446678 |
homeostatic process | GO:0042592 | 126 | 689 | 0.0000324 | 0.0004616 |
second-messenger-mediated signaling | GO:0019932 | 29 | 92 | 0.0000325 | 0.0004616 |
cell cycle process | GO:0022402 | 98 | 504 | 0.0000325 | 0.0004616 |
positive regulation of proteolysis | GO:0045862 | 37 | 134 | 0.0000336 | 0.000475604 |
blood vessel morphogenesis | GO:0048514 | 57 | 248 | 0.0000337 | 0.000476866 |
ribonucleoside monophosphate biosynthetic process | GO:0009156 | 21 | 54 | 0.0000342 | 0.000482191 |
cellular response to DNA damage stimulus | GO:0006974 | 74 | 352 | 0.0000348 | 0.000489794 |
proteasome core complex | GO:0005839 | 12 | 18 | 0.0000356 | 0.000500336 |
purine nucleoside triphosphate biosynthetic process | GO:0009145 | 16 | 33 | 0.0000371 | 0.000519177 |
purine ribonucleoside triphosphate biosynthetic process | GO:0009206 | 16 | 33 | 0.0000371 | 0.000519177 |
enzyme activator activity | GO:0008047 | 46 | 185 | 0.0000379 | 0.000528539 |
circulatory system development | GO:0072359 | 85 | 423 | 0.000039233 | 0.000545465 |
cardiovascular system development | GO:0072358 | 85 | 423 | 0.000039233 | 0.000545465 |
transferase activity, transferring phosphorus-containing groups | GO:0016772 | 98 | 507 | 0.0000396 | 0.000549839 |
regulation of endopeptidase activity | GO:0052548 | 48 | 197 | 0.0000402 | 0.000556112 |
nucleoside diphosphate phosphorylation | GO:0006165 | 19 | 46 | 0.0000415 | 0.000573988 |
response to toxic substance | GO:0009636 | 24 | 69 | 0.0000425 | 0.000586442 |
protein processing | GO:0016485 | 30 | 99 | 0.0000441 | 0.000607015 |
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | GO:0043154 | 18 | 42 | 0.0000448 | 0.000616163 |
cell junction | GO:0030054 | 96 | 496 | 0.0000453 | 0.000618895 |
regulation of anatomical structure morphogenesis | GO:0022603 | 85 | 425 | 0.0000453 | 0.000618895 |
DNA metabolic process | GO:0006259 | 85 | 425 | 0.0000453 | 0.000618895 |
response to chemical | GO:0042221 | 276 | 1753 | 0.0000454 | 0.000618992 |
response to reactive oxygen species | GO:0000302 | 22 | 60 | 0.0000461 | 0.000628252 |
negative regulation of apoptotic process | GO:0043066 | 74 | 356 | 0.0000477 | 0.000647765 |
positive regulation of transcription from RNA polymerase II promoter | GO:0045944 | 98 | 510 | 0.0000482 | 0.000652752 |
protein modification by small protein conjugation | GO:0032446 | 80 | 394 | 0.0000482 | 0.000652752 |
lipid biosynthetic process | GO:0008610 | 60 | 270 | 0.0000489 | 0.000661394 |
regulation of response to stress | GO:0080134 | 99 | 517 | 0.0000496 | 0.000669304 |
organelle assembly | GO:0070925 | 65 | 301 | 0.0000511 | 0.000688151 |
blood circulation | GO:0008015 | 45 | 182 | 0.0000512 | 0.000688151 |
mitophagy | GO:0000422 | 30 | 100 | 0.0000514 | 0.00068846 |
mitochondrion disassembly | GO:0061726 | 30 | 100 | 0.0000514 | 0.00068846 |
threonine-type endopeptidase activity | GO:0004298 | 12 | 19 | 0.000052408 | 0.000699442 |
threonine-type peptidase activity | GO:0070003 | 12 | 19 | 0.000052408 | 0.000699442 |
pyrophosphatase activity | GO:0016462 | 84 | 421 | 0.0000537 | 0.000715347 |
positive regulation of cell death | GO:0010942 | 55 | 241 | 0.0000539 | 0.000716864 |
negative regulation of cysteine-type endopeptidase activity | GO:2000117 | 18 | 43 | 0.0000572 | 0.00075872 |
peroxidase activity | GO:0004601 | 13 | 23 | 0.0000604 | 0.000800391 |
immune effector process | GO:0002252 | 69 | 328 | 0.00006157 | 0.000814302 |
cellular response to endogenous stimulus | GO:0071495 | 92 | 475 | 0.000063 | 0.000831966 |
protein ubiquitination | GO:0016567 | 75 | 366 | 0.0000633 | 0.000834462 |
positive regulation of organelle organization | GO:0010638 | 60 | 273 | 0.0000639 | 0.000840478 |
positive regulation of developmental process | GO:0051094 | 97 | 508 | 0.000064435 | 0.000846085 |
embryo development | GO:0009790 | 91 | 469 | 0.0000652 | 0.000853944 |
collagen metabolic process | GO:0032963 | 15 | 31 | 0.0000657 | 0.000856974 |
multicellular organismal macromolecule metabolic process | GO:0044259 | 15 | 31 | 0.0000657 | 0.000856974 |
ribosomal small subunit biogenesis | GO:0042274 | 19 | 48 | 0.0000657 | 0.000856974 |
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | GO:0016818 | 84 | 424 | 0.0000663 | 0.000862854 |
regulation of cell differentiation | GO:0045595 | 117 | 642 | 0.000069123 | 0.000897987 |
protein import | GO:0017038 | 41 | 162 | 0.0000698 | 0.000904929 |
circulatory system process | GO:0003013 | 45 | 185 | 0.000070992 | 0.000919008 |
positive regulation of apoptotic process | GO:0043065 | 53 | 232 | 0.0000712 | 0.000920598 |
protein maturation | GO:0051604 | 32 | 113 | 0.0000741 | 0.00095263 |
organelle disassembly | GO:1903008 | 32 | 113 | 0.0000741 | 0.00095263 |
sulfur compound metabolic process | GO:0006790 | 38 | 146 | 0.000077 | 0.000987715 |
positive regulation of programmed cell death | GO:0043068 | 53 | 233 | 0.0000783 | 0.00100336 |
carbohydrate derivative catabolic process | GO:1901136 | 21 | 58 | 0.000078761 | 0.001007124 |
protein homodimerization activity | GO:0042803 | 68 | 326 | 0.0000862 | 0.0011006 |
intracellular protein transmembrane import | GO:0044743 | 15 | 32 | 0.0000869 | 0.001107097 |
mitochondrial transmembrane transport | GO:1990542 | 14 | 28 | 0.0000873 | 0.001109255 |
hydrolase activity, acting on acid anhydrides | GO:0016817 | 84 | 428 | 0.0000874 | 0.001109255 |
oxidoreduction coenzyme metabolic process | GO:0006733 | 24 | 73 | 0.0000879 | 0.001114361 |
methyltransferase complex | GO:0034708 | 20 | 54 | 0.0000898 | 0.001136988 |
ribosomal large subunit biogenesis | GO:0042273 | 18 | 45 | 0.0000911 | 0.001151338 |
cellular protein complex assembly | GO:0043623 | 57 | 259 | 0.000093 | 0.001172477 |
apoptotic signaling pathway | GO:0097190 | 64 | 303 | 0.000100696 | 0.001267694 |
monocarboxylic acid metabolic process | GO:0032787 | 57 | 260 | 0.000101527 | 0.001275969 |
regulation of viral process | GO:0050792 | 37 | 143 | 0.000105077 | 0.001316063 |
receptor binding | GO:0005102 | 120 | 670 | 0.00010568 | 0.001321354 |
mitochondrial electron transport, NADH to ubiquinone | GO:0006120 | 10 | 14 | 0.000106776 | 0.001332788 |
precatalytic spliceosome | GO:0071011 | 12 | 21 | 0.000107029 | 0.00133367 |
regulation of mitochondrion organization | GO:0010821 | 29 | 100 | 0.000111645 | 0.001388833 |
purine ribonucleoside diphosphate metabolic process | GO:0009179 | 18 | 46 | 0.000114008 | 0.001403924 |
cysteine-type endopeptidase activity | GO:0004197 | 18 | 46 | 0.000114008 | 0.001403924 |
ribonucleoside diphosphate metabolic process | GO:0009185 | 18 | 46 | 0.000114008 | 0.001403924 |
purine nucleoside diphosphate metabolic process | GO:0009135 | 18 | 46 | 0.000114008 | 0.001403924 |
iron-sulfur cluster binding | GO:0051536 | 18 | 46 | 0.000114008 | 0.001403924 |
metal cluster binding | GO:0051540 | 18 | 46 | 0.000114008 | 0.001403924 |
response to virus | GO:0009615 | 43 | 178 | 0.000115591 | 0.001421037 |
collagen catabolic process | GO:0030574 | 9 | 11 | 0.000116041 | 0.001421788 |
multicellular organism catabolic process | GO:0044243 | 9 | 11 | 0.000116041 | 0.001421788 |
pigment metabolic process | GO:0042440 | 17 | 42 | 0.000126298 | 0.001544886 |
negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 106 | 579 | 0.000127353 | 0.001555189 |
protein transmembrane transport | GO:0071806 | 16 | 38 | 0.000137828 | 0.001671966 |
positive regulation of cell-substrate adhesion | GO:0010811 | 16 | 38 | 0.000137828 | 0.001671966 |
copper ion binding | GO:0005507 | 16 | 38 | 0.000137828 | 0.001671966 |
regulation of transferase activity | GO:0051338 | 75 | 377 | 0.000141369 | 0.001711675 |
preribosome | GO:0030684 | 18 | 47 | 0.000141769 | 0.001711675 |
coenzyme binding | GO:0050662 | 30 | 107 | 0.000141803 | 0.001711675 |
transferase activity, transferring glycosyl groups | GO:0016757 | 39 | 157 | 0.000143806 | 0.001733007 |
metallopeptidase activity | GO:0008237 | 25 | 81 | 0.000144934 | 0.001743734 |
neurogenesis | GO:0022008 | 104 | 568 | 0.000146018 | 0.001753888 |
positive regulation of peptidase activity | GO:0010952 | 23 | 71 | 0.000146335 | 0.001754827 |
regulation of intracellular protein transport | GO:0033157 | 40 | 163 | 0.000148232 | 0.001774078 |
regulation of multi-organism process | GO:0043900 | 46 | 198 | 0.000148425 | 0.001774078 |
transporter activity | GO:0005215 | 127 | 725 | 0.000153883 | 0.001834045 |
vacuolar part | GO:0044437 | 58 | 271 | 0.000153943 | 0.001834045 |
lipid metabolic process | GO:0006629 | 108 | 596 | 0.000155537 | 0.001850028 |
cellular detoxification | GO:1990748 | 17 | 43 | 0.00015851 | 0.001879286 |
cellular oxidant detoxification | GO:0098869 | 17 | 43 | 0.00015851 | 0.001879286 |
regulation of cytoskeleton organization | GO:0051493 | 45 | 193 | 0.000162383 | 0.001922102 |
regulation of catabolic process | GO:0009894 | 46 | 199 | 0.000163755 | 0.001935216 |
negative regulation of multicellular organismal process | GO:0051241 | 84 | 438 | 0.000169569 | 0.002000697 |
lipid binding | GO:0008289 | 61 | 291 | 0.000172279 | 0.002029399 |
antioxidant activity | GO:0016209 | 16 | 39 | 0.000174891 | 0.002056869 |
regulation of protein kinase activity | GO:0045859 | 63 | 304 | 0.000178938 | 0.002101092 |
positive regulation of MAPK cascade | GO:0043410 | 47 | 206 | 0.000181259 | 0.00212493 |
actin filament-based process | GO:0030029 | 58 | 273 | 0.000181673 | 0.002126386 |
extracellular matrix organization | GO:0030198 | 27 | 93 | 0.000186262 | 0.002176625 |
calcium-mediated signaling | GO:0019722 | 19 | 53 | 0.000188067 | 0.002194217 |
cell projection | GO:0042995 | 115 | 647 | 0.000188781 | 0.002199043 |
intracellular protein transmembrane transport | GO:0065002 | 15 | 35 | 0.000189712 | 0.002206385 |
positive regulation of cellular component organization | GO:0051130 | 92 | 493 | 0.000195727 | 0.002272734 |
autophagy | GO:0006914 | 51 | 231 | 0.000197162 | 0.002284396 |
regulation of generation of precursor metabolites and energy | GO:0043467 | 17 | 44 | 0.000197667 | 0.002284396 |
detoxification | GO:0098754 | 17 | 44 | 0.000197667 | 0.002284396 |
proton-transporting ATP synthase complex | GO:0045259 | 12 | 23 | 0.000204525 | 0.002356181 |
protein localization to cell periphery | GO:1990778 | 28 | 99 | 0.000205928 | 0.002364948 |
negative regulation of gene expression | GO:0010629 | 114 | 642 | 0.000207496 | 0.002379218 |
cofactor binding | GO:0048037 | 41 | 172 | 0.000208787 | 0.002390285 |
vacuolar transport | GO:0007034 | 34 | 132 | 0.000210188 | 0.002402573 |
extracellular structure organization | GO:0043062 | 27 | 94 | 0.000215221 | 0.00245245 |
anatomical structure formation involved in morphogenesis | GO:0048646 | 97 | 528 | 0.000216272 | 0.002458737 |
negative regulation of biosynthetic process | GO:0009890 | 113 | 636 | 0.000216444 | 0.002458737 |
protein folding | GO:0006457 | 33 | 127 | 0.000225653 | 0.002559383 |
Wnt signaling pathway | GO:0016055 | 42 | 179 | 0.000234679 | 0.002657635 |
DNA repair | GO:0006281 | 50 | 227 | 0.00023722 | 0.002678132 |
vacuolar membrane | GO:0005774 | 56 | 264 | 0.000240132 | 0.002703932 |
negative regulation of macromolecule biosynthetic process | GO:0010558 | 108 | 604 | 0.000240243 | 0.002703932 |
multicellular organism metabolic process | GO:0044236 | 15 | 36 | 0.000241936 | 0.002718808 |
peptidyl-proline modification | GO:0018208 | 17 | 45 | 0.000244987 | 0.00274888 |
defense response | GO:0006952 | 110 | 618 | 0.000245616 | 0.002751727 |
nuclear body | GO:0016604 | 39 | 162 | 0.000247945 | 0.002773582 |
cell development | GO:0048468 | 141 | 832 | 0.000249079 | 0.002782018 |
activation of immune response | GO:0002253 | 33 | 128 | 0.000254609 | 0.002839451 |
central nervous system development | GO:0007417 | 64 | 315 | 0.000255633 | 0.002846544 |
positive regulation of intracellular protein transport | GO:0090316 | 29 | 106 | 0.000256726 | 0.002854367 |
tRNA metabolic process | GO:0006399 | 31 | 117 | 0.000258409 | 0.002868725 |
cell-cell signaling by wnt | GO:0198738 | 42 | 180 | 0.000259457 | 0.002876007 |
release of cytochrome c from mitochondria | GO:0001836 | 14 | 32 | 0.000260541 | 0.002883664 |
angiogenesis | GO:0001525 | 47 | 210 | 0.000263608 | 0.002913211 |
transmembrane transport | GO:0055085 | 120 | 688 | 0.000266986 | 0.002946093 |
endosome | GO:0005768 | 69 | 348 | 0.000276307 | 0.003042829 |
spliceosomal tri-snRNP complex | GO:0097526 | 12 | 24 | 0.000276583 | 0.003042829 |
lipid localization | GO:0010876 | 36 | 146 | 0.000285647 | 0.003137838 |
cellular response to growth factor stimulus | GO:0071363 | 54 | 254 | 0.000292453 | 0.003206499 |
plasma membrane organization | GO:0007009 | 31 | 118 | 0.000292773 | 0.003206499 |
positive regulation of cellular protein localization | GO:1903829 | 34 | 135 | 0.000298929 | 0.003269036 |
kinase activity | GO:0016301 | 78 | 408 | 0.000307672 | 0.003359635 |
establishment of protein localization to membrane | GO:0090150 | 32 | 124 | 0.000308498 | 0.003363632 |
ossification | GO:0001503 | 40 | 170 | 0.000310239 | 0.003375032 |
negative regulation of nitrogen compound metabolic process | GO:0051172 | 113 | 643 | 0.000310464 | 0.003375032 |
negative regulation of cellular biosynthetic process | GO:0031327 | 111 | 630 | 0.000321398 | 0.003488716 |
regulation of symbiosis, encompassing mutualism through parasitism | GO:0043903 | 37 | 153 | 0.00032688 | 0.003542976 |
substrate-specific transporter activity | GO:0022892 | 109 | 617 | 0.000332484 | 0.003598394 |
pigment granule | GO:0048770 | 20 | 61 | 0.000339232 | 0.003655225 |
melanosome | GO:0042470 | 20 | 61 | 0.000339232 | 0.003655225 |
cysteine-type peptidase activity | GO:0008234 | 26 | 92 | 0.000344184 | 0.00370314 |
protein dimerization activity | GO:0046983 | 103 | 577 | 0.000347464 | 0.003732943 |
negative regulation of phosphorylation | GO:0042326 | 45 | 201 | 0.000349327 | 0.003747469 |
protein complex assembly | GO:0006461 | 105 | 591 | 0.000355013 | 0.003797341 |
protein complex biogenesis | GO:0070271 | 105 | 591 | 0.000355013 | 0.003797341 |
ATP biosynthetic process | GO:0006754 | 13 | 29 | 0.000356731 | 0.003810161 |
snRNA binding | GO:0017069 | 11 | 21 | 0.0003652 | 0.003894534 |
regulation of protein localization | GO:0032880 | 73 | 378 | 0.000365694 | 0.003894534 |
spliceosomal snRNP assembly | GO:0000387 | 12 | 25 | 0.000369078 | 0.003924865 |
multi-organism process | GO:0051704 | 135 | 799 | 0.000371763 | 0.003947697 |
cofactor biosynthetic process | GO:0051188 | 27 | 98 | 0.000375017 | 0.003970739 |
cellular respiration | GO:0045333 | 27 | 98 | 0.000375017 | 0.003970739 |
magnesium ion binding | GO:0000287 | 29 | 109 | 0.000378861 | 0.004005649 |
actin cytoskeleton organization | GO:0030036 | 53 | 251 | 0.000380322 | 0.004015301 |
histone modification | GO:0016570 | 46 | 208 | 0.000380889 | 0.004015506 |
in utero embryonic development | GO:0001701 | 41 | 178 | 0.000382069 | 0.004022154 |
small nucleolar ribonucleoprotein complex | GO:0005732 | 9 | 14 | 0.000416574 | 0.004379112 |
ceramide metabolic process | GO:0006672 | 16 | 43 | 0.000423032 | 0.00443427 |
monocarboxylic acid biosynthetic process | GO:0072330 | 27 | 99 | 0.000428515 | 0.004485331 |
response to growth factor | GO:0070848 | 54 | 259 | 0.000438124 | 0.004579361 |
protein localization to plasma membrane | GO:0072659 | 26 | 94 | 0.000453307 | 0.004731314 |
negative regulation of phosphorus metabolic process | GO:0010563 | 52 | 247 | 0.000455493 | 0.004740622 |
negative regulation of phosphate metabolic process | GO:0045936 | 52 | 247 | 0.000455493 | 0.004740622 |
regulation of response to external stimulus | GO:0032101 | 66 | 336 | 0.000459762 | 0.004778266 |
regulation of transport | GO:0051049 | 126 | 741 | 0.000461609 | 0.004790663 |
regulation of protein catabolic process | GO:0042176 | 34 | 139 | 0.000468504 | 0.004855347 |
positive regulation of endopeptidase activity | GO:0010950 | 21 | 68 | 0.000472804 | 0.004886083 |
regulation of cell-substrate adhesion | GO:0010810 | 21 | 68 | 0.000472804 | 0.004886083 |
U12-type spliceosomal complex | GO:0005689 | 10 | 18 | 0.000474643 | 0.004898183 |
pyridine nucleotide metabolic process | GO:0019362 | 20 | 63 | 0.000477692 | 0.004908901 |
nicotinamide nucleotide metabolic process | GO:0046496 | 20 | 63 | 0.000477692 | 0.004908901 |
protein stabilization | GO:0050821 | 20 | 63 | 0.000477692 | 0.004908901 |
translation initiation factor activity | GO:0003743 | 15 | 39 | 0.000479211 | 0.004917619 |
embryo development ending in birth or egg hatching | GO:0009792 | 59 | 292 | 0.000489205 | 0.005013157 |
endosomal part | GO:0044440 | 37 | 157 | 0.000496659 | 0.005082433 |
regulation of purine nucleotide metabolic process | GO:1900542 | 24 | 84 | 0.000500482 | 0.005114413 |
regulation of cellular localization | GO:0060341 | 65 | 331 | 0.000508263 | 0.005186687 |
cellular carbohydrate metabolic process | GO:0044262 | 31 | 123 | 0.000532935 | 0.005430898 |
regulation of cell-matrix adhesion | GO:0001952 | 14 | 35 | 0.000535988 | 0.005454418 |
covalent chromatin modification | GO:0016569 | 46 | 212 | 0.000542001 | 0.005507966 |
regulation of cell cycle | GO:0051726 | 77 | 411 | 0.000560544 | 0.005680649 |
response to mitochondrial depolarisation | GO:0098780 | 20 | 64 | 0.000563673 | 0.005696599 |
mitophagy in response to mitochondrial depolarization | GO:0098779 | 20 | 64 | 0.000563673 | 0.005696599 |
single-organism carbohydrate catabolic process | GO:0044724 | 19 | 59 | 0.000566514 | 0.005717424 |
cellular amino acid metabolic process | GO:0006520 | 33 | 135 | 0.000568094 | 0.005725481 |
cytoskeletal protein binding | GO:0008092 | 73 | 385 | 0.000574213 | 0.005779198 |
perinuclear region of cytoplasm | GO:0048471 | 51 | 244 | 0.000590928 | 0.005938788 |
viral life cycle | GO:0019058 | 26 | 96 | 0.00059169 | 0.005938788 |
endosome membrane | GO:0010008 | 35 | 147 | 0.000592701 | 0.005940796 |
movement of cell or subcellular component | GO:0006928 | 119 | 698 | 0.000600218 | 0.006007916 |
regulation of establishment of protein localization | GO:0070201 | 64 | 327 | 0.000601814 | 0.006015675 |
regulation of defense response | GO:0031347 | 53 | 257 | 0.000612408 | 0.006113229 |
negative regulation of protein modification process | GO:0031400 | 52 | 251 | 0.000626251 | 0.00623734 |
regulation of canonical Wnt signaling pathway | GO:0060828 | 25 | 91 | 0.000627395 | 0.00623734 |
intrinsic component of organelle membrane | GO:0031300 | 25 | 91 | 0.000627395 | 0.00623734 |
negative regulation of response to external stimulus | GO:0032102 | 27 | 102 | 0.00063137 | 0.006268355 |
proton-transporting two-sector ATPase complex | GO:0016469 | 16 | 45 | 0.000633552 | 0.006281514 |
negative regulation of transferase activity | GO:0051348 | 34 | 142 | 0.00064679 | 0.00640409 |
regulation of translational initiation | GO:0006446 | 17 | 50 | 0.00065841 | 0.006502362 |
cellular response to calcium ion | GO:0071277 | 11 | 23 | 0.000659377 | 0.006502362 |
complement activation | GO:0006956 | 11 | 23 | 0.000659377 | 0.006502362 |
macromitophagy | GO:0000423 | 20 | 65 | 0.000662731 | 0.006517892 |
pyridine-containing compound metabolic process | GO:0072524 | 20 | 65 | 0.000662731 | 0.006517892 |
protein complex binding | GO:0032403 | 63 | 322 | 0.000665376 | 0.006535136 |
regulation of protein serine/threonine kinase activity | GO:0071900 | 42 | 190 | 0.000670219 | 0.006573886 |
chordate embryonic development | GO:0043009 | 58 | 290 | 0.000673238 | 0.006582783 |
negative regulation of protein phosphorylation | GO:0001933 | 41 | 184 | 0.000673821 | 0.006582783 |
cytoplasmic vesicle part | GO:0044433 | 41 | 184 | 0.000673821 | 0.006582783 |
plasma membrane part | GO:0044459 | 161 | 998 | 0.00069181 | 0.006749522 |
phosphoric ester hydrolase activity | GO:0042578 | 43 | 197 | 0.000726609 | 0.007079603 |
ADP metabolic process | GO:0046031 | 15 | 41 | 0.000729798 | 0.007101233 |
melanin metabolic process | GO:0006582 | 8 | 12 | 0.000736545 | 0.007147896 |
SMN-Sm protein complex | GO:0034719 | 8 | 12 | 0.000736545 | 0.007147896 |
glycoprotein metabolic process | GO:0009100 | 39 | 173 | 0.000743208 | 0.007203023 |
cell surface | GO:0009986 | 57 | 285 | 0.000744571 | 0.007206702 |
positive regulation of mitochondrion organization | GO:0010822 | 21 | 71 | 0.000754476 | 0.007292933 |
muscle system process | GO:0003012 | 32 | 132 | 0.000768281 | 0.00741093 |
alpha-amino acid biosynthetic process | GO:1901607 | 16 | 46 | 0.000768706 | 0.00741093 |
chromosome organization | GO:0051276 | 94 | 531 | 0.000774104 | 0.007453166 |
protein polymerization | GO:0051258 | 30 | 121 | 0.000812702 | 0.007814526 |
nucleobase-containing compound kinase activity | GO:0019205 | 12 | 28 | 0.000816365 | 0.007839459 |
positive regulation of transport | GO:0051050 | 70 | 371 | 0.000823658 | 0.007899136 |
nucleoside-triphosphatase activity | GO:0017111 | 73 | 391 | 0.000832138 | 0.007966597 |
RNA phosphodiester bond hydrolysis, endonucleolytic | GO:0090502 | 14 | 37 | 0.000832867 | 0.007966597 |
positive regulation of GTPase activity | GO:0043547 | 45 | 211 | 0.000840624 | 0.008030316 |
endoribonuclease activity, producing 5'-phosphomonoesters | GO:0016891 | 9 | 16 | 0.000850976 | 0.008108068 |
positive regulation of cell-matrix adhesion | GO:0001954 | 9 | 16 | 0.000850976 | 0.008108068 |
regulation of nucleotide metabolic process | GO:0006140 | 24 | 88 | 0.00086824 | 0.008240404 |
integral component of organelle membrane | GO:0031301 | 24 | 88 | 0.00086824 | 0.008240404 |
ATP synthesis coupled proton transport | GO:0015986 | 10 | 20 | 0.000886388 | 0.008380084 |
energy coupled proton transport, down electrochemical gradient | GO:0015985 | 10 | 20 | 0.000886388 | 0.008380084 |
mitochondrial proton-transporting ATP synthase complex | GO:0005753 | 10 | 20 | 0.000886388 | 0.008380084 |
negative regulation of organelle organization | GO:0010639 | 36 | 157 | 0.000895731 | 0.008457505 |
regulation of kinase activity | GO:0043549 | 64 | 333 | 0.00089913 | 0.008478664 |
negative regulation of protein kinase activity | GO:0006469 | 30 | 122 | 0.000908907 | 0.008559843 |
positive regulation of multicellular organismal process | GO:0051240 | 104 | 603 | 0.000916215 | 0.008617597 |
fatty acid biosynthetic process | GO:0006633 | 23 | 83 | 0.000919108 | 0.008633719 |
translation factor activity, RNA binding | GO:0008135 | 19 | 62 | 0.000929754 | 0.008722545 |
endomembrane system organization | GO:0010256 | 46 | 219 | 0.000973948 | 0.00912547 |
defense response to virus | GO:0051607 | 34 | 146 | 0.000976075 | 0.009133714 |
lipid transport | GO:0006869 | 29 | 117 | 0.000986783 | 0.009198672 |
positive regulation of intracellular transport | GO:0032388 | 30 | 123 | 0.001014903 | 0.009448785 |
positive regulation of cell differentiation | GO:0045597 | 64 | 335 | 0.001023992 | 0.009521302 |
mRNA binding | GO:0003729 | 23 | 84 | 0.001052113 | 0.009770378 |
sulfur compound binding | GO:1901681 | 25 | 95 | 0.001054005 | 0.009772764 |
RNA catabolic process | GO:0006401 | 20 | 68 | 0.001055037 | 0.009772764 |
transferase complex, transferring phosphorus-containing groups | GO:0061695 | 33 | 141 | 0.001069192 | 0.009891375 |
organic hydroxy compound metabolic process | GO:1901615 | 39 | 177 | 0.001073119 | 0.009915186 |
protein import into mitochondrial matrix | GO:0030150 | 8 | 13 | 0.001076895 | 0.009937545 |
nucleolar part | GO:0044452 | 15 | 43 | 0.001083661 | 0.009974856 |
oxidoreductase activity, acting on the CH-CH group of donors | GO:0016627 | 15 | 43 | 0.001083661 | 0.009974856 |
sphingolipid metabolic process | GO:0006665 | 19 | 63 | 0.001088519 | 0.009994459 |
carbohydrate catabolic process | GO:0016052 | 19 | 63 | 0.001088519 | 0.009994459 |
centrosome | GO:0005813 | 48 | 233 | 0.001093803 | 0.01003041 |
protein activation cascade | GO:0072376 | 11 | 25 | 0.001128009 | 0.010292552 |
regulation of nucleoside metabolic process | GO:0009118 | 11 | 25 | 0.001128009 | 0.010292552 |
regulation of release of cytochrome c from mitochondria | GO:0090199 | 11 | 25 | 0.001128009 | 0.010292552 |
regulation of ATP metabolic process | GO:1903578 | 11 | 25 | 0.001128009 | 0.010292552 |
epithelial cell differentiation | GO:0030855 | 52 | 259 | 0.001146986 | 0.01045269 |
viral genome replication | GO:0019079 | 13 | 34 | 0.001170111 | 0.010639539 |
small molecule catabolic process | GO:0044282 | 32 | 136 | 0.001170518 | 0.010639539 |
guanyl nucleotide binding | GO:0019001 | 56 | 285 | 0.001173297 | 0.010639539 |
neuron projection | GO:0043005 | 56 | 285 | 0.001173297 | 0.010639539 |
U2 snRNP | GO:0005686 | 9 | 17 | 0.001176738 | 0.010654604 |
cell projection part | GO:0044463 | 58 | 298 | 0.001177867 | 0.010654604 |
microtubule organizing center | GO:0005815 | 59 | 305 | 0.001218323 | 0.011006973 |
endosomal transport | GO:0016197 | 29 | 119 | 0.001232418 | 0.011120603 |
cellular response to oxidative stress | GO:0034599 | 22 | 80 | 0.001275228 | 0.011492737 |
reactive oxygen species metabolic process | GO:0072593 | 24 | 91 | 0.001279999 | 0.011521561 |
cellular response to oxygen-containing compound | GO:1901701 | 61 | 319 | 0.001296406 | 0.011654924 |
melanin biosynthetic process | GO:0042438 | 7 | 10 | 0.001301201 | 0.011655133 |
U4 snRNP | GO:0005687 | 7 | 10 | 0.001301201 | 0.011655133 |
nucleoside diphosphate kinase activity | GO:0004550 | 7 | 10 | 0.001301201 | 0.011655133 |
regulation of cellular component biogenesis | GO:0044087 | 66 | 352 | 0.001304053 | 0.011666096 |
apoptotic mitochondrial changes | GO:0008637 | 18 | 59 | 0.001305609 | 0.011666096 |
mitochondrial intermembrane space | GO:0005758 | 15 | 44 | 0.001308876 | 0.011681038 |
endoribonuclease activity | GO:0004521 | 12 | 30 | 0.001314798 | 0.011705376 |
generation of neurons | GO:0048699 | 91 | 521 | 0.001325941 | 0.011790253 |
cell morphogenesis | GO:0000902 | 92 | 528 | 0.001334819 | 0.011854809 |
cell-substrate adhesion | GO:0031589 | 29 | 120 | 0.00137398 | 0.012187837 |
cell surface receptor signaling pathway involved in cell-cell signaling | GO:1905114 | 44 | 211 | 0.001398397 | 0.012389422 |
response to other organism | GO:0051707 | 73 | 400 | 0.00141408 | 0.012513241 |
TOR complex | GO:0038201 | 6 | 7 | 0.00144177 | 0.012713787 |
TORC2 complex | GO:0031932 | 6 | 7 | 0.00144177 | 0.012713787 |
glycoprotein biosynthetic process | GO:0009101 | 34 | 150 | 0.001443684 | 0.012713787 |
macroautophagy | GO:0016236 | 34 | 150 | 0.001443684 | 0.012713787 |
vesicle-mediated transport | GO:0016192 | 99 | 578 | 0.001448512 | 0.012730837 |
nuclear ubiquitin ligase complex | GO:0000152 | 11 | 26 | 0.001449095 | 0.012730837 |
biological adhesion | GO:0022610 | 100 | 585 | 0.001452888 | 0.012744435 |
regulation of apoptotic signaling pathway | GO:2001233 | 42 | 199 | 0.001454121 | 0.012744435 |
DNA binding | GO:0003677 | 166 | 1055 | 0.001487699 | 0.013023144 |
muscle structure development | GO:0061061 | 50 | 250 | 0.001510676 | 0.0132085 |
cellular component morphogenesis | GO:0032989 | 98 | 572 | 0.001513759 | 0.013219684 |
catalytic step 2 spliceosome | GO:0071013 | 18 | 60 | 0.001527338 | 0.013322386 |
oxidoreductase activity, acting on the CH-NH2 group of donors | GO:0016638 | 8 | 14 | 0.001531937 | 0.013330764 |
U1 snRNP | GO:0005685 | 8 | 14 | 0.001531937 | 0.013330764 |
negative regulation of proteolysis | GO:0045861 | 38 | 175 | 0.001544211 | 0.013421627 |
positive regulation of apoptotic signaling pathway | GO:2001235 | 23 | 87 | 0.00155514 | 0.013500605 |
negative regulation of defense response | GO:0031348 | 17 | 55 | 0.001563985 | 0.013561326 |
late endosome membrane | GO:0031902 | 15 | 45 | 0.001572094 | 0.013615521 |
cell projection organization | GO:0030030 | 87 | 497 | 0.001576605 | 0.013633791 |
regulation of intracellular transport | GO:0032386 | 42 | 200 | 0.001577925 | 0.013633791 |
organelle envelope lumen | GO:0031970 | 16 | 50 | 0.001580993 | 0.01364421 |
response to external biotic stimulus | GO:0043207 | 73 | 402 | 0.001584312 | 0.013656773 |
frizzled binding | GO:0005109 | 9 | 18 | 0.001596151 | 0.013742656 |
vesicle membrane | GO:0012506 | 39 | 182 | 0.001661236 | 0.014276599 |
glycosaminoglycan binding | GO:0005539 | 22 | 82 | 0.001662064 | 0.014276599 |
cell adhesion | GO:0007155 | 99 | 581 | 0.001667286 | 0.01430469 |
negative regulation of cell proliferation | GO:0008285 | 53 | 271 | 0.001702913 | 0.014593263 |
guanyl ribonucleotide binding | GO:0032561 | 55 | 284 | 0.001705595 | 0.014599175 |
negative regulation of peptidase activity | GO:0010466 | 33 | 146 | 0.001746822 | 0.014934616 |
peptidyl-prolyl cis-trans isomerase activity | GO:0003755 | 13 | 36 | 0.001775795 | 0.015146977 |
protein peptidyl-prolyl isomerization | GO:0000413 | 13 | 36 | 0.001775795 | 0.015146977 |
small GTPase mediated signal transduction | GO:0007264 | 49 | 246 | 0.001797498 | 0.01531426 |
GTP binding | GO:0005525 | 53 | 272 | 0.001823705 | 0.015519499 |
chaperone-mediated protein folding | GO:0061077 | 14 | 41 | 0.001849881 | 0.015687593 |
TOR signaling | GO:0031929 | 14 | 41 | 0.001849881 | 0.015687593 |
canonical Wnt signaling pathway | GO:0060070 | 28 | 117 | 0.001857787 | 0.01572784 |
neuron differentiation | GO:0030182 | 82 | 466 | 0.00185892 | 0.01572784 |
regulation of cyclin-dependent protein kinase activity | GO:1904029 | 16 | 51 | 0.001870431 | 0.015806973 |
cytoplasmic ribonucleoprotein granule | GO:0036464 | 20 | 72 | 0.001874785 | 0.015825522 |
ion transport | GO:0006811 | 115 | 696 | 0.001891551 | 0.015948671 |
glutathione peroxidase activity | GO:0004602 | 7 | 11 | 0.001930392 | 0.016257452 |
proteasomal protein catabolic process | GO:0010498 | 39 | 184 | 0.001965447 | 0.016514711 |
reproductive structure development | GO:0048608 | 39 | 184 | 0.001965447 | 0.016514711 |
isomerase activity | GO:0016853 | 26 | 106 | 0.0019815 | 0.01663053 |
regulation of protein transport | GO:0051223 | 58 | 306 | 0.001992011 | 0.016699617 |
dephosphorylation | GO:0016311 | 45 | 222 | 0.002011894 | 0.016823412 |
extracellular matrix binding | GO:0050840 | 10 | 23 | 0.002013666 | 0.016823412 |
proteasome accessory complex | GO:0022624 | 10 | 23 | 0.002013666 | 0.016823412 |
cytoplasmic vesicle membrane | GO:0030659 | 37 | 172 | 0.002028213 | 0.016925644 |
cation transport | GO:0006812 | 88 | 509 | 0.00203426 | 0.016956792 |
amine metabolic process | GO:0009308 | 12 | 32 | 0.002041341 | 0.016996479 |
negative regulation of kinase activity | GO:0033673 | 30 | 130 | 0.002106161 | 0.01751628 |
positive regulation of release of cytochrome c from mitochondria | GO:0090200 | 8 | 15 | 0.002126797 | 0.017593004 |
ribosomal small subunit assembly | GO:0000028 | 8 | 15 | 0.002126797 | 0.017593004 |
neutral amino acid transport | GO:0015804 | 8 | 15 | 0.002126797 | 0.017593004 |
secondary metabolite biosynthetic process | GO:0044550 | 8 | 15 | 0.002126797 | 0.017593004 |
phosphotransferase activity, phosphate group as acceptor | GO:0016776 | 9 | 19 | 0.002127392 | 0.017593004 |
reproductive system development | GO:0061458 | 39 | 185 | 0.002134891 | 0.01763511 |
protein complex disassembly | GO:0043241 | 20 | 73 | 0.002148405 | 0.017726763 |
cis-trans isomerase activity | GO:0016859 | 13 | 37 | 0.00216409 | 0.017816051 |
intrinsic component of mitochondrial membrane | GO:0098573 | 13 | 37 | 0.00216409 | 0.017816051 |
enzyme linked receptor protein signaling pathway | GO:0007167 | 68 | 374 | 0.002177471 | 0.017906094 |
regulation of cellular component movement | GO:0051270 | 62 | 334 | 0.002191884 | 0.018004408 |
cellular response to inorganic substance | GO:0071241 | 16 | 52 | 0.002202867 | 0.018074363 |
chemical homeostasis | GO:0048878 | 78 | 442 | 0.002207929 | 0.018095631 |
regulation of actin filament-based process | GO:0032970 | 32 | 143 | 0.002322509 | 0.018985604 |
regulation of actin cytoskeleton organization | GO:0032956 | 30 | 131 | 0.002324292 | 0.018985604 |
single organism reproductive process | GO:0044702 | 81 | 464 | 0.002380345 | 0.019421811 |
positive regulation of cell proliferation | GO:0008284 | 61 | 329 | 0.002420816 | 0.019730053 |
ATPase activity, coupled | GO:0042623 | 36 | 168 | 0.002442118 | 0.019881555 |
positive regulation of protein kinase activity | GO:0045860 | 35 | 162 | 0.002476566 | 0.020139618 |
locomotion | GO:0040011 | 105 | 632 | 0.002494171 | 0.020260301 |
pigment biosynthetic process | GO:0046148 | 12 | 33 | 0.002511939 | 0.020382036 |
regulation of immune response | GO:0050776 | 49 | 251 | 0.002555974 | 0.020716399 |
negative regulation of cellular amide metabolic process | GO:0034249 | 16 | 53 | 0.002583075 | 0.020889835 |
negative regulation of translation | GO:0017148 | 16 | 53 | 0.002583075 | 0.020889835 |
regulation of muscle system process | GO:0090257 | 19 | 69 | 0.002609632 | 0.021063887 |
macromolecular complex disassembly | GO:0032984 | 21 | 80 | 0.002610347 | 0.021063887 |
vacuole organization | GO:0007033 | 24 | 97 | 0.002622789 | 0.021117775 |
positive regulation of cytoskeleton organization | GO:0051495 | 24 | 97 | 0.002622789 | 0.021117775 |
cardiac muscle contraction | GO:0060048 | 15 | 48 | 0.002639895 | 0.021185662 |
mitochondrial membrane organization | GO:0007006 | 15 | 48 | 0.002639895 | 0.021185662 |
cellular response to metal ion | GO:0071248 | 15 | 48 | 0.002639895 | 0.021185662 |
heart contraction | GO:0060047 | 22 | 86 | 0.002741138 | 0.021974086 |
muscle contraction | GO:0006936 | 26 | 109 | 0.002745122 | 0.021981977 |
phosphotransferase activity, alcohol group as acceptor | GO:0016773 | 65 | 358 | 0.002759358 | 0.022049318 |
regulation of cellular respiration | GO:0043457 | 7 | 12 | 0.002771588 | 0.022049318 |
relaxation of muscle | GO:0090075 | 7 | 12 | 0.002771588 | 0.022049318 |
proton-transporting ATP synthase complex, coupling factor F(o) | GO:0045263 | 7 | 12 | 0.002771588 | 0.022049318 |
eukaryotic translation initiation factor 3 complex | GO:0005852 | 7 | 12 | 0.002771588 | 0.022049318 |
oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | GO:0016641 | 7 | 12 | 0.002771588 | 0.022049318 |
nuclease activity | GO:0004518 | 27 | 115 | 0.002782734 | 0.022102237 |
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | GO:0016893 | 9 | 20 | 0.002790306 | 0.022102237 |
proteasome regulatory particle | GO:0005838 | 9 | 20 | 0.002790306 | 0.022102237 |
proton-transporting two-sector ATPase complex, proton-transporting domain | GO:0033177 | 9 | 20 | 0.002790306 | 0.022102237 |
ribonucleoprotein granule | GO:0035770 | 20 | 75 | 0.002797457 | 0.022111077 |
endonuclease activity | GO:0004519 | 20 | 75 | 0.002797457 | 0.022111077 |
response to inorganic substance | GO:0010035 | 30 | 133 | 0.002819072 | 0.022257911 |
4 iron, 4 sulfur cluster binding | GO:0051539 | 11 | 29 | 0.002884483 | 0.022711884 |
anaphase-promoting complex | GO:0005680 | 8 | 16 | 0.002888969 | 0.022711884 |
snoRNA binding | GO:0030515 | 8 | 16 | 0.002888969 | 0.022711884 |
microtubule-based process | GO:0007017 | 53 | 279 | 0.002899648 | 0.022771402 |
placenta development | GO:0001890 | 19 | 70 | 0.002985786 | 0.023397708 |
cell junction assembly | GO:0034329 | 19 | 70 | 0.002985786 | 0.023397708 |
lipid homeostasis | GO:0055088 | 16 | 54 | 0.003016142 | 0.023610333 |
regulation of cell adhesion | GO:0030155 | 50 | 260 | 0.003025653 | 0.023659507 |
DNA-templated transcription, elongation | GO:0006354 | 12 | 34 | 0.003067127 | 0.023958254 |
cellular response to acid chemical | GO:0071229 | 15 | 49 | 0.003107131 | 0.024219098 |
negative regulation of nucleobase-containing compound metabolic process | GO:0045934 | 99 | 595 | 0.003123885 | 0.024323811 |
drug binding | GO:0008144 | 13 | 39 | 0.003150365 | 0.024477971 |
collagen trimer | GO:0005581 | 13 | 39 | 0.003150365 | 0.024477971 |
glutamine family amino acid metabolic process | GO:0009064 | 14 | 44 | 0.003157174 | 0.024504888 |
intrinsic component of endoplasmic reticulum membrane | GO:0031227 | 18 | 65 | 0.003171102 | 0.02458695 |
tRNA processing | GO:0008033 | 20 | 76 | 0.003179113 | 0.024623002 |
response to biotic stimulus | GO:0009607 | 74 | 422 | 0.003227675 | 0.024972728 |
non-canonical Wnt signaling pathway | GO:0035567 | 10 | 25 | 0.003261994 | 0.025211637 |
negative regulation of cellular component organization | GO:0051129 | 53 | 281 | 0.003293863 | 0.02543112 |
transport vesicle | GO:0030133 | 32 | 147 | 0.003342187 | 0.025777058 |
striated muscle contraction | GO:0006941 | 17 | 60 | 0.003347605 | 0.025791698 |
actin cytoskeleton | GO:0015629 | 40 | 197 | 0.003352557 | 0.025802714 |
alcohol metabolic process | GO:0006066 | 27 | 117 | 0.003407989 | 0.026179074 |
fatty acid metabolic process | GO:0006631 | 36 | 172 | 0.003408603 | 0.026179074 |
aldehyde catabolic process | GO:0046185 | 6 | 9 | 0.003470105 | 0.026523284 |
2'-deoxyribonucleotide metabolic process | GO:0009394 | 6 | 9 | 0.003470105 | 0.026523284 |
snoRNA metabolic process | GO:0016074 | 6 | 9 | 0.003470105 | 0.026523284 |
heart process | GO:0003015 | 22 | 88 | 0.00347152 | 0.026523284 |
nuclear speck | GO:0016607 | 22 | 88 | 0.00347152 | 0.026523284 |
muscle tissue development | GO:0060537 | 34 | 160 | 0.003540203 | 0.027019863 |
membrane lipid metabolic process | GO:0006643 | 23 | 94 | 0.003575107 | 0.027257867 |
actin filament organization | GO:0007015 | 33 | 154 | 0.003598235 | 0.027405684 |
oxidoreductase activity, acting on the CH-NH group of donors | GO:0016645 | 9 | 21 | 0.00360627 | 0.027438361 |
lamellipodium | GO:0030027 | 18 | 66 | 0.003633326 | 0.027615542 |
enzyme inhibitor activity | GO:0004857 | 42 | 211 | 0.003673682 | 0.027864462 |
monosaccharide metabolic process | GO:0005996 | 25 | 106 | 0.003709425 | 0.028080787 |
secretory granule membrane | GO:0030667 | 12 | 35 | 0.003717533 | 0.028080787 |
glial cell development | GO:0021782 | 12 | 35 | 0.003717533 | 0.028080787 |
regulation of calcium-mediated signaling | GO:0050848 | 12 | 35 | 0.003717533 | 0.028080787 |
immune response-regulating signaling pathway | GO:0002764 | 26 | 112 | 0.003745041 | 0.028247211 |
axon | GO:0030424 | 29 | 130 | 0.00375241 | 0.028247211 |
G-protein coupled receptor binding | GO:0001664 | 29 | 130 | 0.00375241 | 0.028247211 |
response to extracellular stimulus | GO:0009991 | 27 | 118 | 0.003762697 | 0.028247211 |
protein glycosylation | GO:0006486 | 27 | 118 | 0.003762697 | 0.028247211 |
macromolecule glycosylation | GO:0043413 | 27 | 118 | 0.003762697 | 0.028247211 |
ncRNA 3'-end processing | GO:0043628 | 8 | 17 | 0.003848024 | 0.028778545 |
channel inhibitor activity | GO:0016248 | 8 | 17 | 0.003848024 | 0.028778545 |
preribosome, large subunit precursor | GO:0030687 | 8 | 17 | 0.003848024 | 0.028778545 |
cell cycle phase transition | GO:0044770 | 34 | 161 | 0.003849184 | 0.028778545 |
positive regulation of cysteine-type endopeptidase activity | GO:2001056 | 17 | 61 | 0.003854893 | 0.028791847 |
regulation of extracellular matrix organization | GO:1903053 | 7 | 13 | 0.00386738 | 0.028849952 |
cell-matrix adhesion | GO:0007160 | 19 | 72 | 0.003874485 | 0.028849952 |
regulation of viral life cycle | GO:1903900 | 19 | 72 | 0.003874485 | 0.028849952 |
developmental process involved in reproduction | GO:0003006 | 52 | 277 | 0.003879567 | 0.028858466 |
mitotic cell cycle | GO:0000278 | 67 | 378 | 0.003936115 | 0.029249409 |
transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 44 | 225 | 0.003974533 | 0.029504967 |
peroxiredoxin activity | GO:0051920 | 5 | 6 | 0.004002847 | 0.02968508 |
protein transporter activity | GO:0008565 | 16 | 56 | 0.004062744 | 0.030068412 |
regulation of protein kinase B signaling | GO:0051896 | 16 | 56 | 0.004062744 | 0.030068412 |
response to acid chemical | GO:0001101 | 20 | 78 | 0.004073529 | 0.030117809 |
epithelial cell proliferation | GO:0050673 | 35 | 168 | 0.004094195 | 0.030209632 |
proteasome-mediated ubiquitin-dependent protein catabolic process | GO:0043161 | 35 | 168 | 0.004094195 | 0.030209632 |
regulation of angiogenesis | GO:0045765 | 25 | 107 | 0.004113146 | 0.030288464 |
skin development | GO:0043588 | 25 | 107 | 0.004113146 | 0.030288464 |
nuclear-transcribed mRNA catabolic process | GO:0000956 | 15 | 51 | 0.004245904 | 0.03120335 |
epithelial cell apoptotic process | GO:1904019 | 11 | 31 | 0.004357231 | 0.031925434 |
cellular aldehyde metabolic process | GO:0006081 | 11 | 31 | 0.004357231 | 0.031925434 |
regulation of viral genome replication | GO:0045069 | 11 | 31 | 0.004357231 | 0.031925434 |
organelle fission | GO:0048285 | 52 | 279 | 0.004391708 | 0.03213756 |
cell cycle G1/S phase transition | GO:0044843 | 19 | 73 | 0.004394955 | 0.03213756 |
cell motility | GO:0048870 | 93 | 561 | 0.004454933 | 0.032459492 |
localization of cell | GO:0051674 | 93 | 561 | 0.004454933 | 0.032459492 |
regulation of protein targeting | GO:1903533 | 30 | 138 | 0.004463073 | 0.032459492 |
mitochondrial ATP synthesis coupled electron transport | GO:0042775 | 12 | 36 | 0.004474422 | 0.032459492 |
glycolytic process | GO:0006096 | 12 | 36 | 0.004474422 | 0.032459492 |
positive regulation of canonical Wnt signaling pathway | GO:0090263 | 12 | 36 | 0.004474422 | 0.032459492 |
ATP generation from ADP | GO:0006757 | 12 | 36 | 0.004474422 | 0.032459492 |
integral component of mitochondrial membrane | GO:0032592 | 12 | 36 | 0.004474422 | 0.032459492 |
ATPase activity | GO:0016887 | 42 | 214 | 0.004551105 | 0.032964522 |
response to nutrient levels | GO:0031667 | 25 | 108 | 0.004553036 | 0.032964522 |
hemopoiesis | GO:0030097 | 66 | 374 | 0.004568266 | 0.033042139 |
guanyl-nucleotide exchange factor activity | GO:0005085 | 20 | 79 | 0.004593536 | 0.03319215 |
growth factor binding | GO:0019838 | 16 | 57 | 0.004687978 | 0.033774648 |
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | GO:0043280 | 16 | 57 | 0.004687978 | 0.033774648 |
negative regulation of transcription, DNA-templated | GO:0045892 | 85 | 506 | 0.004694606 | 0.033789172 |
growth | GO:0040007 | 70 | 402 | 0.004713026 | 0.033878609 |
ubiquitin-like protein transferase activity | GO:0019787 | 43 | 221 | 0.004719381 | 0.033878609 |
neuron development | GO:0048666 | 64 | 361 | 0.004724144 | 0.033878609 |
protein kinase B signaling | GO:0043491 | 18 | 68 | 0.004725527 | 0.033878609 |
cell migration | GO:0016477 | 87 | 521 | 0.004903338 | 0.035112252 |
negative regulation of nucleic acid-templated transcription | GO:1903507 | 86 | 514 | 0.004907185 | 0.035112252 |
erythrocyte differentiation | GO:0030218 | 15 | 52 | 0.004931137 | 0.035180566 |
protein depolymerization | GO:0051261 | 15 | 52 | 0.004931137 | 0.035180566 |
centrosome organization | GO:0051297 | 15 | 52 | 0.004931137 | 0.035180566 |
glycosylation | GO:0070085 | 28 | 127 | 0.004984601 | 0.035492878 |
epithelial cell migration | GO:0010631 | 24 | 103 | 0.005004683 | 0.035508536 |
cell morphogenesis involved in differentiation | GO:0000904 | 56 | 308 | 0.005029348 | 0.035508536 |
tissue migration | GO:0090130 | 25 | 109 | 0.005031535 | 0.035508536 |
MLL1/2 complex | GO:0044665 | 8 | 18 | 0.005035263 | 0.035508536 |
protein K11-linked ubiquitination | GO:0070979 | 8 | 18 | 0.005035263 | 0.035508536 |
purine-containing compound catabolic process | GO:0072523 | 8 | 18 | 0.005035263 | 0.035508536 |
negative regulation of Ras protein signal transduction | GO:0046580 | 8 | 18 | 0.005035263 | 0.035508536 |
negative regulation of small GTPase mediated signal transduction | GO:0051058 | 8 | 18 | 0.005035263 | 0.035508536 |
Wnt-protein binding | GO:0017147 | 8 | 18 | 0.005035263 | 0.035508536 |
MLL1 complex | GO:0071339 | 8 | 18 | 0.005035263 | 0.035508536 |
deoxyribonucleotide metabolic process | GO:0009262 | 6 | 10 | 0.005045512 | 0.035512453 |
deoxyribose phosphate metabolic process | GO:0019692 | 6 | 10 | 0.005045512 | 0.035512453 |
integral component of endoplasmic reticulum membrane | GO:0030176 | 17 | 63 | 0.005059708 | 0.035544086 |
RNA 3'-end processing | GO:0031123 | 14 | 47 | 0.005137726 | 0.036057582 |
regulation of system process | GO:0044057 | 35 | 171 | 0.005193632 | 0.036415067 |
skeletal system development | GO:0001501 | 42 | 216 | 0.005230266 | 0.036636861 |
quinone binding | GO:0048038 | 7 | 14 | 0.005262622 | 0.036688139 |
pyrimidine nucleoside triphosphate metabolic process | GO:0009147 | 7 | 14 | 0.005262622 | 0.036688139 |
nucleotide kinase activity | GO:0019201 | 7 | 14 | 0.005262622 | 0.036688139 |
oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor | GO:0016646 | 7 | 14 | 0.005262622 | 0.036688139 |
peptidase activator activity | GO:0016504 | 7 | 14 | 0.005262622 | 0.036688139 |
cellular response to reactive oxygen species | GO:0034614 | 13 | 42 | 0.005286655 | 0.036770076 |
extracellular matrix component | GO:0044420 | 12 | 37 | 0.005349652 | 0.037118274 |
regulation of TOR signaling | GO:0032006 | 12 | 37 | 0.005349652 | 0.037118274 |
regulation of defense response to virus | GO:0050688 | 18 | 69 | 0.005365061 | 0.037146841 |
G1/S transition of mitotic cell cycle | GO:0000082 | 18 | 69 | 0.005365061 | 0.037146841 |
reproductive process | GO:0022414 | 84 | 502 | 0.005368978 | 0.037146841 |
cell division | GO:0051301 | 45 | 236 | 0.005378265 | 0.037175986 |
intrinsic component of plasma membrane | GO:0031226 | 96 | 587 | 0.005442657 | 0.037585626 |
head development | GO:0060322 | 48 | 256 | 0.005459239 | 0.037664638 |
regulation of I-kappaB kinase/NF-kappaB signaling | GO:0043122 | 27 | 122 | 0.005508111 | 0.037930384 |
regulation of Wnt signaling pathway | GO:0030111 | 27 | 122 | 0.005508111 | 0.037930384 |
epithelium migration | GO:0090132 | 24 | 104 | 0.005538305 | 0.038042728 |
homeostasis of number of cells | GO:0048872 | 26 | 116 | 0.005540002 | 0.038042728 |
regulation of vasculature development | GO:1901342 | 26 | 116 | 0.005540002 | 0.038042728 |
reproduction | GO:0000003 | 84 | 503 | 0.005611897 | 0.038500347 |
muscle organ development | GO:0007517 | 31 | 147 | 0.005685982 | 0.038972115 |
negative regulation of catabolic process | GO:0009895 | 15 | 53 | 0.005703289 | 0.039017738 |
exopeptidase activity | GO:0008238 | 15 | 53 | 0.005703289 | 0.039017738 |
regulation of cell cycle process | GO:0010564 | 45 | 237 | 0.005740455 | 0.039235368 |
cellular protein complex disassembly | GO:0043624 | 17 | 64 | 0.005768281 | 0.03938881 |
nucleoside phosphate catabolic process | GO:1901292 | 9 | 23 | 0.005789458 | 0.039474674 |
inflammatory response | GO:0006954 | 48 | 257 | 0.005810613 | 0.03956725 |
monovalent inorganic cation transport | GO:0015672 | 51 | 277 | 0.005823194 | 0.039616104 |
outer membrane | GO:0019867 | 21 | 87 | 0.005938412 | 0.040325062 |
organelle outer membrane | GO:0031968 | 21 | 87 | 0.005938412 | 0.040325062 |
nucleoside-triphosphatase regulator activity | GO:0060589 | 26 | 117 | 0.006086234 | 0.04121427 |
regulation of inflammatory response | GO:0050727 | 26 | 117 | 0.006086234 | 0.04121427 |
osteoblast differentiation | GO:0001649 | 23 | 99 | 0.006093119 | 0.041222791 |
coated membrane | GO:0048475 | 16 | 59 | 0.006173704 | 0.041690993 |
membrane coat | GO:0030117 | 16 | 59 | 0.006173704 | 0.041690993 |
positive regulation of immune response | GO:0050778 | 39 | 199 | 0.006201538 | 0.041762576 |
regulation of protein complex disassembly | GO:0043244 | 13 | 43 | 0.006212803 | 0.041762576 |
regulation of cyclin-dependent protein serine/threonine kinase activity | GO:0000079 | 13 | 43 | 0.006212803 | 0.041762576 |
endoplasmic reticulum lumen | GO:0005788 | 13 | 43 | 0.006212803 | 0.041762576 |
protease binding | GO:0002020 | 13 | 43 | 0.006212803 | 0.041762576 |
prefoldin complex | GO:0016272 | 5 | 7 | 0.00625136 | 0.041944793 |
positive regulation of protein kinase B signaling | GO:0051897 | 12 | 38 | 0.006355619 | 0.042521476 |
regulation of protein localization to plasma membrane | GO:1903076 | 11 | 33 | 0.006372128 | 0.042521476 |
maturation of SSU-rRNA | GO:0030490 | 11 | 33 | 0.006372128 | 0.042521476 |
regulation of protein localization to cell periphery | GO:1904375 | 11 | 33 | 0.006372128 | 0.042521476 |
sphingolipid biosynthetic process | GO:0030148 | 11 | 33 | 0.006372128 | 0.042521476 |
nucleotide catabolic process | GO:0009166 | 8 | 19 | 0.006483309 | 0.043145511 |
U4/U6 x U5 tri-snRNP complex | GO:0046540 | 8 | 19 | 0.006483309 | 0.043145511 |
neutral amino acid transmembrane transporter activity | GO:0015175 | 8 | 19 | 0.006483309 | 0.043145511 |
activation of protein kinase activity | GO:0032147 | 20 | 82 | 0.006491675 | 0.043161978 |
negative regulation of endopeptidase activity | GO:0010951 | 28 | 130 | 0.00651939 | 0.043306955 |
regulation of muscle contraction | GO:0006937 | 15 | 54 | 0.006570015 | 0.043571635 |
nuclear division | GO:0000280 | 48 | 259 | 0.006571128 | 0.043571635 |
regulation of anatomical structure size | GO:0090066 | 41 | 213 | 0.006643289 | 0.044010287 |
actin polymerization or depolymerization | GO:0008154 | 22 | 94 | 0.00669956 | 0.044283778 |
double-strand break repair | GO:0006302 | 22 | 94 | 0.00669956 | 0.044283778 |
mitotic cell cycle phase transition | GO:0044772 | 31 | 149 | 0.006702704 | 0.044283778 |
positive regulation of I-kappaB kinase/NF-kappaB signaling | GO:0043123 | 23 | 100 | 0.006740673 | 0.044494514 |
regulation of heart contraction | GO:0008016 | 18 | 71 | 0.006856426 | 0.045217852 |
negative regulation of RNA biosynthetic process | GO:1902679 | 86 | 522 | 0.006936035 | 0.045652066 |
ribonuclease activity | GO:0004540 | 14 | 49 | 0.006940958 | 0.045652066 |
blastocyst development | GO:0001824 | 14 | 49 | 0.006940958 | 0.045652066 |
nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 29 | 137 | 0.006986027 | 0.045899322 |
glucose 6-phosphate metabolic process | GO:0051156 | 7 | 15 | 0.007003609 | 0.045899322 |
U5 snRNP | GO:0005682 | 7 | 15 | 0.007003609 | 0.045899322 |
INO80-type complex | GO:0097346 | 7 | 15 | 0.007003609 | 0.045899322 |
regulation of cell motility | GO:2000145 | 56 | 314 | 0.007040697 | 0.045940755 |
regulation of cellular response to stress | GO:0080135 | 43 | 227 | 0.007043342 | 0.045940755 |
P-P-bond-hydrolysis-driven transmembrane transporter activity | GO:0015405 | 16 | 60 | 0.007047551 | 0.045940755 |
mRNA catabolic process | GO:0006402 | 16 | 60 | 0.007047551 | 0.045940755 |
primary active transmembrane transporter activity | GO:0015399 | 16 | 60 | 0.007047551 | 0.045940755 |
positive regulation of cell junction assembly | GO:1901890 | 6 | 11 | 0.007087863 | 0.046039691 |
methylosome | GO:0034709 | 6 | 11 | 0.007087863 | 0.046039691 |
protein K48-linked deubiquitination | GO:0071108 | 6 | 11 | 0.007087863 | 0.046039691 |
eukaryotic 43S preinitiation complex | GO:0016282 | 6 | 11 | 0.007087863 | 0.046039691 |
chromatin binding | GO:0003682 | 41 | 214 | 0.007103602 | 0.046101055 |
Golgi membrane | GO:0000139 | 39 | 201 | 0.007127748 | 0.046216822 |
protein domain specific binding | GO:0019904 | 44 | 234 | 0.007228001 | 0.046825429 |
regulation of establishment of protein localization to mitochondrion | GO:1903747 | 13 | 44 | 0.007263478 | 0.047013698 |
positive regulation of immune system process | GO:0002684 | 60 | 342 | 0.007319799 | 0.047336421 |
nuclear membrane | GO:0031965 | 25 | 113 | 0.007383626 | 0.047665045 |
phosphatase activity | GO:0016791 | 30 | 144 | 0.007435315 | 0.047956475 |
late endosome | GO:0005770 | 23 | 101 | 0.007443674 | 0.047968163 |
cellular response to decreased oxygen levels | GO:0036294 | 12 | 39 | 0.007505191 | 0.048026667 |
growth cone | GO:0030426 | 12 | 39 | 0.007505191 | 0.048026667 |
site of polarized growth | GO:0030427 | 12 | 39 | 0.007505191 | 0.048026667 |
negative regulation of inflammatory response | GO:0050728 | 12 | 39 | 0.007505191 | 0.048026667 |
histone methyltransferase complex | GO:0035097 | 12 | 39 | 0.007505191 | 0.048026667 |
dicarboxylic acid metabolic process | GO:0043648 | 12 | 39 | 0.007505191 | 0.048026667 |
response to calcium ion | GO:0051592 | 12 | 39 | 0.007505191 | 0.048026667 |
cellular response to hypoxia | GO:0071456 | 12 | 39 | 0.007505191 | 0.048026667 |
erythrocyte homeostasis | GO:0034101 | 15 | 55 | 0.007539253 | 0.048142878 |
microtubule organizing center organization | GO:0031023 | 15 | 55 | 0.007539253 | 0.048142878 |
substrate-specific transmembrane transporter activity | GO:0022891 | 86 | 524 | 0.007543063 | 0.048142878 |
ERBB signaling pathway | GO:0038127 | 11 | 34 | 0.007621012 | 0.048555789 |
centrosome cycle | GO:0007098 | 11 | 34 | 0.007621012 | 0.048555789 |
positive regulation of establishment of protein localization | GO:1904951 | 39 | 202 | 0.007632619 | 0.048587489 |
hydrolase activity, acting on glycosyl bonds | GO:0016798 | 18 | 72 | 0.007719004 | 0.04909474 |